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DTaP-IPV//PRP~T and Hepatitis B vaccine
DTaP-IPV//PRP~T and Hepatitis B vaccine is a Combination vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Prevention of diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b infection, and hepatitis B in infants and children. Also known as: Pentaxim™, Euvax B®.
This combination vaccine stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B.
This combination vaccine stimulates the immune system to produce antibodies against diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b, and hepatitis B. Used for Prevention of diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b infection, and hepatitis B in infants and children.
At a glance
| Generic name | DTaP-IPV//PRP~T and Hepatitis B vaccine |
|---|---|
| Also known as | Pentaxim™, Euvax B® |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | Combination vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease Prevention |
| Phase | Phase 3 |
Mechanism of action
The vaccine contains inactivated toxoids (diphtheria and tetanus), acellular pertussis antigens, inactivated poliovirus, conjugated Haemophilus influenzae type b polysaccharide, and recombinant hepatitis B surface antigen. These components trigger both humoral and cellular immune responses, leading to the production of protective antibodies and memory cells against these six pathogens.
Approved indications
- Prevention of diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b infection, and hepatitis B in infants and children
Common side effects
- Injection site pain, redness, or swelling
- Fever
- Irritability or fussiness
- Drowsiness
- Loss of appetite
Key clinical trials
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants (PHASE1, PHASE2)
- Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers (PHASE3)
- Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico (PHASE3)
- Anti-Hep B Antibodies at Age 9 to 10 Years After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine. (PHASE3)
- DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants (PHASE3)
- Immunogenicity and Safety of Sanofi Pasteur's Combined Vaccine Given as a Three-Dose Primary Series at 2, 3,4 Months of Age and Followed by a Booster Dose Given at 16 to 17 Months of Age in Vietnamese Infants Who Previously Received a Dose of Hepatitis B Vaccine at Birth or Within 1 Week After Birth (PHASE3)
- Anti-Hep B Antibodies at Age 12 to 18 Months After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine Concomitantly With Prevnar® at 2, 4 and 6 Months of Age (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTaP-IPV//PRP~T and Hepatitis B vaccine CI brief — competitive landscape report
- DTaP-IPV//PRP~T and Hepatitis B vaccine updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about DTaP-IPV//PRP~T and Hepatitis B vaccine
What is DTaP-IPV//PRP~T and Hepatitis B vaccine?
How does DTaP-IPV//PRP~T and Hepatitis B vaccine work?
What is DTaP-IPV//PRP~T and Hepatitis B vaccine used for?
Who makes DTaP-IPV//PRP~T and Hepatitis B vaccine?
Is DTaP-IPV//PRP~T and Hepatitis B vaccine also known as anything else?
What drug class is DTaP-IPV//PRP~T and Hepatitis B vaccine in?
What development phase is DTaP-IPV//PRP~T and Hepatitis B vaccine in?
What are the side effects of DTaP-IPV//PRP~T and Hepatitis B vaccine?
Related
- Drug class: All Combination vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease Prevention
- Indication: Drugs for Prevention of diphtheria, tetanus, pertussis, poliomyelitis, Haemophilus influenzae type b infection, and hepatitis B in infants and children
- Also known as: Pentaxim™, Euvax B®
- Compare: DTaP-IPV//PRP~T and Hepatitis B vaccine vs similar drugs
- Pricing: DTaP-IPV//PRP~T and Hepatitis B vaccine cost, discount & access