What are the marketed Antimuscarinic and beta-3 adrenergic agonist combination drugs?

Marketed Antimuscarinic and beta-3 adrenergic agonist combination drugs include tolterodine , mirabegron, Enlon-Plus, DICYCLOMINE, IV Neostigmine Methylsulfate + Atropine Sulphate, Solifenacin + Mirabegron.

Antimuscarinic and beta-3 adrenergic agonist combination

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

5 marketed 2 in Phase 3

This page covers all Antimuscarinic and beta-3 adrenergic agonist combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Muscarinic M3 receptor and beta-3 adrenergic receptor, Muscarinic acetylcholine receptors, Muscarinic receptors.

Targets

Muscarinic M3 receptor and beta-3 adrenergic receptor · Muscarinic acetylcholine receptors · Muscarinic receptors · Acetylcholinesterase (neostigmine); Muscarinic acetylcholine receptors (atropine) · M3 muscarinic receptor (solifenacin) and beta-3 adrenergic receptor (mirabegron) · M3 receptor · M3 muscarinic receptor

Marketed (5)

tolterodine , mirabegron · Far Eastern Memorial Hospital · Urology
Tolterodine and mirabegron work together to reduce overactive bladder symptoms through complementary pathways: tolterodine blocks muscarinic receptors to decrease bladder contractions, while mirabegron activates beta-3 adrenergic receptors to relax the detrusor muscle.
Enlon-Plus · Alcon Labs Inc · Other
Atropine antagonizes muscarine-like actions of acetylcholine through competitive antagonism at peripheral muscarinic receptors.
DICYCLOMINE · Gastroenterology
Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract via a dual mechanism: anticholinergic effects at acetylcholine receptors and direct smooth muscle relaxation.
IV Neostigmine Methylsulfate + Atropine Sulphate · Damanhour Teaching Hospital · Neurology
Neostigmine inhibits acetylcholinesterase to increase acetylcholine levels, while atropine blocks muscarinic receptors to prevent cholinergic toxicity.
Solifenacin + Mirabegron · University of Aarhus · Urology / Neurology
Solifenacin and mirabegron work synergistically to reduce overactive bladder symptoms by blocking muscarinic receptors (solifenacin) and activating beta-3 adrenergic receptors (mirabegron) to decrease detrusor muscle contractions and increase bladder capacity.

Phase 3 pipeline (2)

imidafenacin, KRP-197/ONO-8025 · Ono Pharmaceutical Co. Ltd · Urology
Imidafenacin is an antimuscarinic agent that acts as a selective M3 receptor antagonist.
Mictonetten 5 mg, coated tablet · APOGEPHA Arzneimittel GmbH · Urology
Mictonetten is a muscarinic M3 receptor antagonist that reduces bladder muscle contractions to treat overactive bladder symptoms.

Patent intelligence

antimuscarinic patent landscape — aggregated cliff calendar, attackable patents, originator estates