Who are Synera patch for 12hrs/day's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Levobupivacaine wound infiltration, Lidocaine-chlorprocaine combination, Lidocaine HCl 1%, Lidocaine injection flushed, Lidocaine infiltration, Ropivacaine/Fentanyl.

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Last reviewed 2026-06-10 · How we verify

Synera patch for 12hrs/day — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Synera patch for 12hrs/day (Synera patch for 12hrs/day) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical local anesthetic combination. Area: Pain Management / Dermatology.

marketed Topical local anesthetic combination Voltage-gated sodium channels Pain Management / Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Synera patch for 12hrs/day (Synera patch for 12hrs/day) — International Clinical Research Institute. Synera patch delivers lidocaine and tetracaine through the skin to provide topical anesthesia by blocking sodium channels in nerve fibers.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Synera patch for 12hrs/day TARGET	Synera patch for 12hrs/day	International Clinical Research Institute	marketed	Topical local anesthetic combination	Voltage-gated sodium channels
Levobupivacaine wound infiltration	Levobupivacaine wound infiltration	University of Genova	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Lidocaine-chlorprocaine combination	Lidocaine-chlorprocaine combination	Hadassah Medical Organization	marketed	Local anesthetic combination	Voltage-gated sodium channels
Lidocaine HCl 1%	Lidocaine HCl 1%	HaEmek Medical Center, Israel	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine injection flushed	Lidocaine injection flushed	Wake Forest University Health Sciences	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine infiltration	Lidocaine infiltration	Vrije Universiteit Brussel	marketed	Local anesthetic	Voltage-gated sodium channels
Ropivacaine/Fentanyl	Ropivacaine/Fentanyl	National Institute for Tuberculosis and Lung Diseases, Poland	marketed	Local anesthetic with opioid analgesic combination	Voltage-gated sodium channels (ropivacaine); mu opioid receptor (fentanyl)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical local anesthetic combination class)

International Clinical Research Institute · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Synera patch for 12hrs/day — Competitive Intelligence Brief. https://druglandscape.com/ci/synera-patch-for-12hrs-day. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing