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Synera patch for 12hrs/day
Synera patch for 12hrs/day is a Topical local anesthetic combination Small molecule drug developed by International Clinical Research Institute. It is currently FDA-approved for Topical anesthesia for minor procedures (e.g., venipuncture, dermatological procedures), Localized pain relief.
Synera patch delivers lidocaine and tetracaine through the skin to provide topical anesthesia by blocking sodium channels in nerve fibers.
The Synera patch is a small molecule used to treat epicondylitis of the elbow. It is applied for 12 hours a day, with its efficacy compared to naproxen sodium in clinical trials.
At a glance
| Generic name | Synera patch for 12hrs/day |
|---|---|
| Sponsor | International Clinical Research Institute |
| Drug class | Topical local anesthetic combination |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Pain Management / Dermatology |
| Phase | FDA-approved |
Mechanism of action
The patch combines two local anesthetics—lidocaine and tetracaine—that penetrate the skin and reversibly inhibit sodium influx in nerve cell membranes, preventing depolarization and blocking pain signal transmission. The 12-hour daily application provides localized numbing suitable for minor procedures or pain relief without systemic absorption.
Approved indications
- Topical anesthesia for minor procedures (e.g., venipuncture, dermatological procedures)
- Localized pain relief
Common side effects
- Skin irritation or erythema at application site
- Allergic contact dermatitis
- Temporary blanching or edema
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Synera patch for 12hrs/day CI brief — competitive landscape report
- Synera patch for 12hrs/day updates RSS · CI watch RSS
- International Clinical Research Institute portfolio CI
Frequently asked questions about Synera patch for 12hrs/day
What is Synera patch for 12hrs/day?
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Related
- Drug class: All Topical local anesthetic combination drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: International Clinical Research Institute — full pipeline
- Therapeutic area: All drugs in Pain Management / Dermatology
- Indication: Drugs for Topical anesthesia for minor procedures (e.g., venipuncture, dermatological procedures)
- Indication: Drugs for Localized pain relief
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing