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Remifentanil, Dexmedetomidine, and Desflurane — Competitive Intelligence Brief
Target snapshot
Remifentanil, Dexmedetomidine, and Desflurane (Remifentanil, Dexmedetomidine, and Desflurane) — The Cooper Health System. This is a combination of three anesthetic agents that work synergistically: remifentanil (opioid agonist), dexmedetomidine (alpha-2 adrenergic agonist), and desflurane (volatile anesthetic) to produce sedation, analgesia, and unconsciousness for surgical procedures.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Remifentanil, Dexmedetomidine, and Desflurane TARGET | Remifentanil, Dexmedetomidine, and Desflurane | The Cooper Health System | marketed | General anesthetic combination | Mu-opioid receptor (remifentanil), alpha-2 adrenergic receptor (dexmedetomidine), GABA and other CNS targets (desflurane) | |
| Remifentanil, propofol and citanest | Remifentanil, propofol and citanest | University of Aarhus | marketed | General anesthetic combination | Mu opioid receptor (remifentanil); GABA-A receptor (propofol); Voltage-gated sodium channels (prilocaine) | |
| Sevoflurane+Propofol | Sevoflurane+Propofol | Huazhong University of Science and Technology | marketed | General anesthetic combination | GABA-A receptor | |
| Anesthesia maintenance , propofol,remifentanil,cisatracurium | Anesthesia maintenance , propofol,remifentanil,cisatracurium | Second Affiliated Hospital of Xi'an Jiaotong University | marketed | General anesthetic combination (GABA-A agonist + opioid + neuromuscular blocker) | GABA-A receptor (propofol); mu-opioid receptor (remifentanil); nicotinic acetylcholine receptor at neuromuscular junction (cisatracurium) | |
| Ketofol as induction agent | Ketofol as induction agent | Fayoum University Hospital | marketed | General anesthetic combination | NMDA receptor antagonist (ketamine) and GABA-A receptor agonist (propofol) | |
| Remifentanil, Propofol, and Desflurane | Remifentanil, Propofol, and Desflurane | The Cooper Health System | marketed | General anesthetic combination | Mu-opioid receptor (remifentanil); GABA-A receptor (propofol); multiple ion channels and neurotransmitter receptors (desflurane) | |
| propofol,remifentanil,cis atracurium | propofol,remifentanil,cis atracurium | Tang-Du Hospital | marketed | General anesthetic combination (GABA agonist + opioid + neuromuscular blocker) | GABA-A receptor (propofol); mu-opioid receptor (remifentanil); nicotinic acetylcholine receptor at neuromuscular junction (cisatracurium) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (General anesthetic combination class)
- The Cooper Health System · 2 drugs in this class
- Fayoum University Hospital · 1 drug in this class
- Huazhong University of Science and Technology · 1 drug in this class
- Memorial Sloan Kettering Cancer Center · 1 drug in this class
- The Cleveland Clinic · 1 drug in this class
- University of Aarhus · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Remifentanil, Dexmedetomidine, and Desflurane — Competitive Intelligence Brief. https://druglandscape.com/ci/remifentanil-dexmedetomidine-and-desflurane. Accessed 2026-05-18.
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