Who are Ketofol as induction agent's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Remifentanil, propofol and citanest, Sevoflurane+Propofol, Anesthesia maintenance , propofol,remifentanil,cisatracurium, Remifentanil, Dexmedetomidine, and Desflurane, propofol，remifentanil，cis atracurium, Remifentanil, Propofol, and Desflurane.

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Last reviewed 2026-06-10 · How we verify

Ketofol as induction agent — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ketofol as induction agent (Ketofol as induction agent) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: General anesthetic combination. Area: Anesthesiology.

marketed General anesthetic combination NMDA receptor antagonist (ketamine) and GABA-A receptor agonist (propofol) Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

Ketofol as induction agent (Ketofol as induction agent) — Fayoum University Hospital. Ketofol is a combination of ketamine and propofol that produces rapid anesthesia by blocking NMDA receptors and enhancing GABAergic inhibition simultaneously.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Ketofol as induction agent TARGET	Ketofol as induction agent	Fayoum University Hospital	marketed	General anesthetic combination	NMDA receptor antagonist (ketamine) and GABA-A receptor agonist (propofol)
Remifentanil, propofol and citanest	Remifentanil, propofol and citanest	University of Aarhus	marketed	General anesthetic combination	Mu opioid receptor (remifentanil); GABA-A receptor (propofol); Voltage-gated sodium channels (prilocaine)
Sevoflurane+Propofol	Sevoflurane+Propofol	Huazhong University of Science and Technology	marketed	General anesthetic combination	GABA-A receptor
Anesthesia maintenance , propofol,remifentanil,cisatracurium	Anesthesia maintenance , propofol,remifentanil,cisatracurium	Second Affiliated Hospital of Xi'an Jiaotong University	marketed	General anesthetic combination (GABA-A agonist + opioid + neuromuscular blocker)	GABA-A receptor (propofol); mu-opioid receptor (remifentanil); nicotinic acetylcholine receptor at neuromuscular junction (cisatracurium)
Remifentanil, Dexmedetomidine, and Desflurane	Remifentanil, Dexmedetomidine, and Desflurane	The Cooper Health System	marketed	General anesthetic combination	Mu-opioid receptor (remifentanil), alpha-2 adrenergic receptor (dexmedetomidine), GABA and other CNS targets (desflurane)
propofol，remifentanil，cis atracurium	propofol，remifentanil，cis atracurium	Tang-Du Hospital	marketed	General anesthetic combination (GABA agonist + opioid + neuromuscular blocker)	GABA-A receptor (propofol); mu-opioid receptor (remifentanil); nicotinic acetylcholine receptor at neuromuscular junction (cisatracurium)
Remifentanil, Propofol, and Desflurane	Remifentanil, Propofol, and Desflurane	The Cooper Health System	marketed	General anesthetic combination	Mu-opioid receptor (remifentanil); GABA-A receptor (propofol); multiple ion channels and neurotransmitter receptors (desflurane)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (General anesthetic combination class)

The Cooper Health System · 2 drugs in this class
Fayoum University Hospital · 1 drug in this class
Huazhong University of Science and Technology · 1 drug in this class
Memorial Sloan Kettering Cancer Center · 1 drug in this class
The Cleveland Clinic · 1 drug in this class
University of Aarhus · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ketofol as induction agent — Competitive Intelligence Brief. https://druglandscape.com/ci/ketofol-as-induction-agent. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing