How many drugs were approved in 2028?

Drug Landscape currently tracks no drug approvals with a first_approval_date in 2028.

Which patents expired in 2028?

163 patents on currently-marketed drugs reached their listed expiry date in 2028. Each entry links back to the drug profile with full Orange Book data.

What Phase 3 readouts happened in 2028?

No Phase 3 trials have completion dates in 2028.

Where does this data come from?

Approvals from FDA Drugs@FDA, EMA EPAR, MHRA, and PMDA. Patent data from FDA Orange Book + USPTO PAIR. Trial data from ClinicalTrials.gov. Updates daily.

2028 in pharma — approvals, patent cliffs, Phase 3 readouts

Every FDA approval, patent expiry, and pivotal Phase 3 readout tracked for 2028: 0 approvals, 163 patent expiries, 0 Phase 3 milestones.

2026 2027 2028 2029

FDA / EMA / MHRA approvals (0)

No entries tracked.

Patent expiries (163)

Sun Jan 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Mitozytrex · 9539241 · US · Compound
Fri Jan 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Deltasone · 8168218 · US · Formulation
Wed Jan 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Derma-Smoothe/Fs · 7998108 · US · Formulation
Wed Jan 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8216180 · US
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 9289432 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 8217033 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 8809322 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 8217033 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 9289432 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 9687495 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 9687495 · US · Formulation
Tue Jan 18 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Versed · 8809322 · US · Formulation
Sun Jan 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Natazia · 8153616 · US
Tue Feb 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Omnaris · 8371292 · US
Wed Feb 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Metro I.V. In Plastic Container · 8877792 · US · Formulation
Sat Feb 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Breo Ellipta · 8161968 · US
Sun Feb 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Risperdal · 10010612 · US · Formulation
Sun Feb 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Risperdal · 9180197 · US · Formulation
Sun Feb 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Risperdal · 9186413 · US · Method of Use
Sun Feb 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Risperdal · 10376590 · US · Method of Use
Sun Feb 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Risperdal · 11712475 · US · Method of Use
Sun Feb 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Risperdal · 11013809 · US · Formulation
Thu Feb 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — LASMIDITAN SUCCINATE · 7423050 · US
Sat Feb 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Metro I.V. In Plastic Container · 7893097 · US · Formulation
Thu Mar 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Pradaxa · 7866474*PED · US
Sun Mar 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Naloxone Hydrochloride · 7947017 · US · Formulation
Sun Mar 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Bupivacaine Hydrochloride And Epinephrine · 7947017 · US · Formulation
Sun Mar 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Epipen · 7947017 · US · Formulation
Mon Mar 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Proventil · 7837235 · US
Tue Mar 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8361972 · US
Wed Mar 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Lupron · 9617303 · US
Wed Mar 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Leuprolide Acetate · 9617303 · US
Wed Mar 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Cystagon · 8026284*PED · US
Sat Mar 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8439864 · US
Sat Mar 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 9320853 · US
Sun Mar 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Combipres · 9066936 · US
Sun Mar 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Proventil · 8651103 · US
Sun Mar 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Edarbi · 9066936 · US
Sun Apr 02 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Breo Ellipta · 9333310*PED · US
Tue Apr 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Topamax · 8298576 · US · Formulation
Fri Apr 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Arthrotec · 8252838 · US
Sun Apr 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Breo Ellipta · 8113199*PED · US
Tue Apr 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 8778373 · US · Method of Use
Tue Apr 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 9408858 · US · Method of Use
Tue Apr 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 9925147 · US · Formulation
Tue Apr 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 8207149 · US · Method of Use
Tue Apr 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 9498486 · US · Method of Use
Tue Apr 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 11154509 · US · Method of Use
Mon May 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Clozaril · 8057811 · US · Formulation
Sun May 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Dovonex · 8263580 · US · Formulation
Fri May 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8758292*PED · US
Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Zosyn · 7129232 · US
Mon May 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Zerbaxa · 7129232 · US
Tue May 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Zuragard · 9629368 · US
Tue May 23 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Zuragard · 8703828 · US
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 12403095 · US · Formulation
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 11419823 · US · Formulation
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 10166190 · US · Formulation
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 10864199 · US · Method of Use
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 12083103 · US · Method of Use
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 11110081 · US · Method of Use
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 11123331 · US · Method of Use
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 9549918 · US · Formulation
Tue May 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — TELAPREVIR · 8431615 · US
Wed May 31 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Differin · 7998467 · US · Formulation
Sun Jun 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Spy Agent Green Kit · 8185176 · US · Method of Use
Tue Jun 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rowasa · 8217083 · US
Tue Jun 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rowasa · 8436051 · US
Tue Jun 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — MESALAMINE · 8217083 · US · Formulation
Tue Jun 06 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — MESALAMINE · 8436051 · US · Formulation
Sat Jun 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Kisqali · 8324225 · US
Tue Jun 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — PATIROMER · 8147873 · US
Thu Jun 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Acid Reflux Relief · 7687075 · US
Thu Jun 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Osmoprep · 7687075 · US
Tue Jun 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Metro I.V. In Plastic Container · 8658678 · US · Method of Use
Sat Jul 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Afinitor · 9006224 · US · Method of Use
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Femring · 9730900 · US · Method of Use
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Femring · 9833419 · US · Formulation
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Estring · 9724310 · US · Compound
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Estring · 9730900 · US · Method of Use
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Estring · 9833419 · US · Formulation
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Femring · 9724310 · US · Compound
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Estrace · 9730900 · US · Method of Use
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Estrace · 9833419 · US · Formulation
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Estrace · 9724310 · US · Compound
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ortho-Novum 10/11-21 · 8747888 · US
Mon Jul 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ortho-Novum 10/11-21 · 9050348 · US
Wed Jul 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8216180*PED · US
Sat Jul 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Fluticasone Furoate/Umeclidinium/Vilanterol (FUV) · 8347879 · US · Formulation
Wed Jul 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 8361488 · US · Formulation
Tue Aug 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Tradjenta · 7579449 · US
Thu Aug 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Vantobra · 7795316 · US
Sat Aug 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Breo Ellipta · 8161968*PED · US
Mon Aug 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Androstenolone Acetate · 8629129 · US · Formulation
Sat Aug 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Duramorph Pf · 10314788 · US · Formulation
Sat Aug 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — MS Contin · 7955619 · US · Formulation
Sat Aug 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — MS Contin · 10314788 · US · Formulation
Sat Aug 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — OXYCODONE HYDROCHLORIDE · 7955619 · US
Sat Aug 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — OXYCODONE HYDROCHLORIDE · 10314788 · US
Sat Aug 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Duramorph Pf · 7955619 · US · Formulation
Tue Aug 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Locametz · 11369590 · US
Tue Aug 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Pluvicto · 11318121 · US
Tue Aug 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Pluvicto · 10406240 · US
Thu Aug 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — GIVOSIRAN SODIUM · 10131907 · US
Sat Aug 26 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ortho-Novum 10/11-21 · 8246978 · US
Sun Aug 27 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Rayaldee · 8426391 · US · Method of Use
Tue Aug 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Camptosar · 8147867 · US · Compound
Tue Aug 29 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Camptosar · 8147867 · US
Wed Aug 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 8664239 · US · Method of Use
Wed Aug 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prograf · 8685998 · US · Formulation
Fri Sep 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Topicort · 8277780 · US · Formulation
Thu Sep 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Proventil · 8132712 · US
Thu Sep 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Beconase Aq · 8132712 · US
Tue Sep 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Vantobra · 8869794 · US
Tue Sep 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Tobi · 8869794 · US · Formulation
Sat Sep 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Vizamyl · 8916131 · US
Sun Sep 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Viekira Pak (Copackaged) · 8501238 · US
Sun Sep 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Keppra · 7858122 · US · Formulation
Thu Sep 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8361972*PED · US
Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 8439864*PED · US
Mon Sep 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Byetta · 9320853*PED · US
Mon Oct 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — OxyContin · 7771707 · US · Formulation
Tue Oct 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Renacidin · 8450338 · US
Tue Oct 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prepopik · 8450338 · US
Tue Oct 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Prepopik · 8481083 · US
Tue Oct 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Renacidin · 8481083 · US
Wed Oct 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Glycopyrrolate · 8479730 · US · Formulation
Wed Oct 11 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Cuvposa · 8479730 · US
Sun Oct 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Fluticasone Furoate/Umeclidinium/Vilanterol (FUV) · 8147461 · US · Formulation
Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Inqovi · 8618075 · US
Mon Oct 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Inqovi · 9567363 · US
Fri Oct 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Cuvposa · 8182838 · US
Fri Oct 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Glycopyrrolate · 8182838 · US · Formulation
Tue Oct 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Tygacil · 8975242 · US
Tue Oct 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Tygacil · 8975242 · US
Mon Oct 30 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Naloxone Hydrochloride · 7749194 · US · Formulation
Sun Nov 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Temovate · 8460641 · US · Formulation
Tue Nov 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Derma-Smoothe/Fs · 9849027 · US · Formulation
Thu Nov 09 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Viekira Pak (Copackaged) · 9139536 · US
Fri Nov 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Tegretol · 9629797 · US · Method of Use
Fri Nov 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Tegretol · 9770407 · US · Formulation
Sun Nov 12 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Pulmicort Respules · 11357859 · US · Method of Use
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Acetaminophen · 9610265 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Acetaminophen · 10383834 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Acetaminophen · 9987238 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 11013761 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 10682376 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 10695367 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 10933090 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 11013762 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 10925896 · US
Mon Nov 13 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ferrlecit · 10925897 · US
Wed Nov 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Pulmicort Respules · 10293052 · US · Formulation
Sat Nov 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Naloxone Hydrochloride · 8231573 · US · Formulation
Sat Nov 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Epipen · 8231573 · US · Formulation
Sat Nov 25 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Bupivacaine Hydrochloride And Epinephrine · 8231573 · US · Formulation
Mon Dec 04 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — GIVOSIRAN SODIUM · 8828956 · US
Tue Dec 05 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Ortho-Novum 10/11-21 · 7855190 · US
Thu Dec 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Cuvposa · 9265900 · US
Thu Dec 07 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Glycopyrrolate · 9265900 · US · Formulation
Thu Dec 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Suprax · 9233112 · US · Formulation
Sat Dec 16 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — Abilify · 9119554 · US · Formulation
Tue Dec 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time) — TELOTRISTAT ETIPRATE · 8653094 · US · Method of Use

Phase 3 readouts (0)

No entries tracked.