Potassium voltage-gated channel subfamily H member 2 — Drug Target

All drugs that target Potassium voltage-gated channel subfamily H member 2 — marketed and clinical-stage. Includes 15 drug classes acting on this target.

Drug classes

Atypical Antipsychotic · Diarylquinoline Antimycobacterial · High Risk QT Prolonging Agents · terodiline · Macrolide · grepafloxacin · Hepatitis C Virus NS5A Inhibitor · Cholinergic Muscarinic Antagonist · Macrolide Antimicrobial [EPC] · Antiarrhythmic [EPC] · Antimalarial · Antiarrhythmic

Marketed (20)

• Invega Sustenna · Johnson & Johnson · Atypical Antipsychotic · Metabolic
  Invega Sustenna works by blocking a specific channel in the brain that helps regulate electrical activity.
• Sirturo · Janssen Therap · Diarylquinoline Antimycobacterial · Infectious Disease
  Sirturo works by blocking the potassium voltage-gated channel subfamily H member 2, which is essential for the survival of Mycobacterium tuberculosis bacteria.
• Hismanal · High Risk QT Prolonging Agents · Other
• BECLABUVIR · Bristol-Myers Squibb · Infectious Disease
• Dl-Terodiline · terodiline · Urology
• Benzamycin · Pfizer · Macrolide · Immunology
• Trisenox · Cephalon · High Risk QT Prolonging Agents · Oncology
• Rukobia · GSK · Immunology
  Rukobia works by blocking the potassium voltage-gated channel subfamily H member 2, which is involved in the replication of the human immunodeficiency virus 1.
• Tomefloxacin · Otsuka · grepafloxacin · Infectious Disease
• Daklinza · Bristol-Myers Squibb · Hepatitis C Virus NS5A Inhibitor · Oncology
• Urispas · Cholinergic Muscarinic Antagonist · Pain
• Biaxin · Generic (originally Abbott/AbbVie) · Macrolide Antimicrobial [EPC] · Infectious Disease
  Clarithromycin is a macrolide antimicrobial drug.
• Orlaam · Roxane · High Risk QT Prolonging Agents · Cardiovascular
• Tikosyn · Pfizer · Antiarrhythmic [EPC] · Cardiovascular
  Tikosyn works by blocking the potassium channels in the heart, which helps to regulate the heart's rhythm.
• Halfan · GSK · Antimalarial · Rare Disease
• Tambocor · Antiarrhythmic · Cardiovascular
• Coartem · Novartis · Antimalarial [EPC] · Rare Disease
  Coartem Tablets, a combination of artemether and lumefantrine, act as an antimalarial agent.
• Sparcin · High Risk QT Prolonging Agents · Infectious Disease
• Ketek · Sanofi · Ketolide Antibacterial · Infectious Disease
• Corvert · Pfizer · Antiarrhythmic · Cardiovascular

Phase 2 pipeline (1)

• Nopoxamine · myrtecaine · Cardiovascular
  Nopoxamine works by blocking potassium channels in the heart to help stabilize heart rhythm.