Antiarrhythmic

This page covers all Antiarrhythmic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Potassium voltage-gated channel subfamily H member 2, Potassium channels, sodium channels, potassium channels, calcium channels.

Targets

Potassium voltage-gated channel subfamily H member 2 · Potassium channels · sodium channels, potassium channels, calcium channels · Histamine H1 receptor · Muscarinic acetylcholine receptor M2 · 5-hydroxytryptamine receptor 2B · AV node, bundle of His · hERG channel · I(f) channel · Unknown

Marketed (9)

• Corvert · Pfizer · Cardiovascular
• (B) T-V7 · National Taiwan University Hospital · Cardiovascular
  T-V7 is a medication used to treat atrial fibrillation.
• Cordarone · Pfizer · Cardiovascular
  Amiodarone, a class III antiarrhythmic, blocks sodium, potassium, and calcium channels, prolongs cardiac action potentials, and has vasodilatory effects.
• Norpace Cr · Pfizer · Cardiovascular
• PL 1 · Technical University of Munich · Cardiovascular
  PL 1 is a medication used to treat atrial fibrillation.
• Quinidine Gluconate · Eli Lilly · Neuroscience
  Quinidine Gluconate works by blocking the M2 muscarinic acetylcholine receptor, which helps regulate heart rhythm.
• Mexitil · Boehringer Ingelheim · Metabolic
  Mexitil works by blocking abnormal electrical signals in the heart to restore a normal heartbeat.
• Tambocor · Cardiovascular
• (C) D-V14 · National Taiwan University Hospital · Cardiovascular
  D-V14 is a medication used to treat atrial fibrillation.

Phase 3 pipeline (4)

• PVC (twice weekly) · Wyeth is now a wholly owned subsidiary of Pfizer · Cardiovascular
  PVC works by blocking the action of certain electrical signals in the heart, helping to regulate its rhythm.
• O.M.T · Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Cardiovascular
  O.M.T is a medication used to treat atrial fibrillation.
• combination of Ivabradine and bisoprolol · Ain Shams University · Cardiovascular
  Ivabradine works by inhibiting the I(f) channel in the sinoatrial node, reducing heart rate, while bisoprolol acts as a beta-1 selective adrenergic receptor blocker, further reducing heart rate and contractility.
• RENESSANS · MTI Medical Private Limited, Pakistan · Cardiovascular
  RENESSANS is a medication used to treat atrial fibrillation.