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Urispas (FLAVOXATE)
Urispas (Flavoxate) is a cholinergic muscarinic antagonist, a small molecule drug that targets the potassium voltage-gated channel subfamily H member 2. It was originally developed and is currently owned by a pharmaceutical company. Urispas is used to treat various urinary tract symptoms such as dysuria, increased urinary frequency, and nocturia. The drug is off-patent and has multiple generic manufacturers. As a cholinergic muscarinic antagonist, Urispas works by blocking the action of acetylcholine at muscarinic receptors in the bladder, reducing muscle spasms and improving urinary flow.
At a glance
| Generic name | FLAVOXATE |
|---|---|
| Drug class | Cholinergic Muscarinic Antagonist |
| Target | Potassium voltage-gated channel subfamily H member 2 |
| Modality | Small molecule |
| Therapeutic area | Pain |
| Phase | FDA-approved |
| First approval | 1970 |
Approved indications
- Dysuria
- Increased Urinary Frequency
- Nocturia
- Suprapubic pain
- Urgent desire to urinate
- Urinary Tract Irritation
- Urinary incontinence
Common side effects
- Nausea
- Vomiting
- Dry mouth
- Vertigo
- Headache
- Mental confusion
- Drowsiness
- Nervousness
- Tachycardia
- Palpitation
- Urticaria
- Eosinophilia
Drug interactions
- potassium chloride
Key clinical trials
- A Relative Bioavailability Study of 100 mg Flavoxate Hydrochloride Tablets Under Fasting Conditions (PHASE1)
- Etoricoxib With Flavoxate for Reducing Morphine Requirement After Transurethral Prostatectomy (TURP) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Urispas CI brief — competitive landscape report
- Urispas updates RSS · CI watch RSS