D2 receptor — Drug Target

All drugs that target D2 receptor — marketed and clinical-stage. Includes 6 drug classes acting on this target.

Drug classes

Atypical antipsychotic · dopamine agonist · Dopamine antagonist · Dopamine D2 receptor antagonist · Second-line antipsychotic · Dopamine receptor antagonist

Marketed (1)

• A-prexa · HK inno.N Corporation · Atypical antipsychotic · Psychiatry
  A-prexa is an antipsychotic medication that works by blocking dopamine receptors in the brain.

Phase 3 pipeline (7)

• Ropinirole XL (formerly CR) · GlaxoSmithKline · dopamine agonist · Neurology
  Ropinirole XL is a dopamine agonist that works by stimulating dopamine receptors in the brain.
• Sulpiride use · Hospital de Clinicas de Porto Alegre · Dopamine antagonist · Psychiatry
  Sulpiride is a dopamine antagonist that acts on D2 receptors in the brain.
• OPC-12759 · Otsuka Pharmaceutical Co., Ltd. · Dopamine D2 receptor antagonist · Psychiatry
  OPC-12759 is a selective dopamine D2 receptor antagonist.
• ropinirole PR/XR · GlaxoSmithKline · dopamine agonist · Neurology
  Ropinirole PR/XR is a dopamine agonist that mimics the action of dopamine in the brain, helping to regulate movement and reduce symptoms of Parkinson's disease.
• Second-line Antipsychotics · Dr. Inge Winter · Second-line antipsychotic · Psychiatry
  Second-line antipsychotics work by blocking dopamine receptors in the brain, reducing psychotic symptoms.
• metoclopramide intravenous · University Hospital, Bordeaux · Dopamine antagonist · Gastroenterology
  Metoclopramide works by blocking dopamine receptors in the gastrointestinal tract, which helps to increase motility and relieve symptoms of gastroparesis.
• ropinirole immediate release · GlaxoSmithKline · dopamine agonist · Neurology
  Ropinirole is a dopamine agonist that works by activating dopamine receptors in the brain.

Phase 2 pipeline (2)

• ACT-539313 · Idorsia Pharmaceuticals Ltd. · Dopamine D2 receptor antagonist · Psychiatry
  ACT-539313 is a selective dopamine D2 receptor antagonist.
• AP09004 · Intec Pharma Ltd. · Dopamine receptor antagonist · Neurology
  AP09004 is a drug that targets the dopamine receptor D2.