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metoclopramide intravenous
metoclopramide intravenous is a Dopamine antagonist Small molecule drug developed by University Hospital, Bordeaux. It is currently in Phase 3 development for Treatment of gastroparesis. Also known as: Primperan.
Metoclopramide works by blocking dopamine receptors in the gastrointestinal tract, which helps to increase motility and relieve symptoms of gastroparesis.
Metoclopramide works by blocking dopamine receptors in the gastrointestinal tract, which helps to increase motility and relieve symptoms of gastroparesis. Used for Treatment of gastroparesis.
At a glance
| Generic name | metoclopramide intravenous |
|---|---|
| Also known as | Primperan |
| Sponsor | University Hospital, Bordeaux |
| Drug class | Dopamine antagonist |
| Target | D2 receptor |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | Phase 3 |
Mechanism of action
By blocking dopamine D2 receptors, metoclopramide increases the release of acetylcholine, a neurotransmitter that stimulates gastrointestinal motility. This helps to speed up the movement of food through the digestive system and relieve symptoms of gastroparesis, such as nausea, vomiting, and abdominal pain.
Approved indications
- Treatment of gastroparesis
Common side effects
- Dystonia
- Parkinsonism
- Akathisia
- Somnolence
- Headache
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Fatigue
Key clinical trials
- A Study Evaluating the Safety, Tolerability and Pharmacokinetics of ASY202 in Healthy Adults (PHASE1)
- NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer. (PHASE1)
- Effect of Dexmedetomidine on the Quality of Recovery in Parturients Undergoing Elective Caesarean Sections (PHASE4)
- Gastric Volumes by US in Term Parturients Undergoing CS With and Without Metoclopramide (PHASE4)
- Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room (PHASE3)
- Non-opioid Anesthesia Based on Thoracic Paravertebral Block During Laparoscopic Sleeve Gastrectomy (NA)
- The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise (NA)
- Comparison Between Intravenous Ondanosteron and Metclopromide Versus Ondanesteron and Dexamethasone Effects on the Prevention of Postoperative Nausea and Vomiting in Cesarean Section (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- metoclopramide intravenous CI brief — competitive landscape report
- metoclopramide intravenous updates RSS · CI watch RSS
- University Hospital, Bordeaux portfolio CI
Frequently asked questions about metoclopramide intravenous
What is metoclopramide intravenous?
How does metoclopramide intravenous work?
What is metoclopramide intravenous used for?
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Is metoclopramide intravenous also known as anything else?
What drug class is metoclopramide intravenous in?
What development phase is metoclopramide intravenous in?
What are the side effects of metoclopramide intravenous?
What does metoclopramide intravenous target?
Related
- Drug class: All Dopamine antagonist drugs
- Target: All drugs targeting D2 receptor
- Manufacturer: University Hospital, Bordeaux — full pipeline
- Therapeutic area: All drugs in Gastroenterology
- Indication: Drugs for Treatment of gastroparesis
- Also known as: Primperan
- Compare: metoclopramide intravenous vs similar drugs
- Pricing: metoclopramide intravenous cost, discount & access