What are Dopamine antagonist drugs?

Dopamine antagonist drugs are pharmacologic agents that share a common mechanism (typically targeting D2/D3 receptor). 0 are currently marketed, with 5 more in clinical development.

Dopamine antagonist

0 marketed 4 in Phase 3 1 in Phase 2

This page covers all Dopamine antagonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting D2/D3 receptor, D2 receptor, Dopamine D2/D3 receptors.

Targets

D2/D3 receptor · D2 receptor · Dopamine D2/D3 receptors · Dopamine D2 receptor

Phase 3 pipeline (4)

Experimental: Arm A: DRL_RI · Dr. Reddy's Laboratories Limited · Psychiatry
This drug is a dopamine receptor D2/D3 antagonist.
metoclopramide intravenous · University Hospital, Bordeaux · Gastroenterology
Metoclopramide works by blocking dopamine receptors in the gastrointestinal tract, which helps to increase motility and relieve symptoms of gastroparesis.
Sulpiride use · Hospital de Clinicas de Porto Alegre · Psychiatry
Sulpiride is a dopamine antagonist that acts on D2 receptors in the brain.
Amisulpride IV Prevention · Benaroya Research Institute · Immunology
Amisulpride is a selective dopamine D2/D3 receptor antagonist that blocks dopamine signaling to prevent or reduce disease progression.

Phase 2 pipeline (1)

Current Domperidone · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · Gastrointestinal
Current Domperidone acts as a dopamine D2 receptor antagonist.