What are Dopamine agonist drugs?

Dopamine agonist drugs are pharmacologic agents that share a common mechanism (typically targeting Dopamine receptors (D1-D5)). 7 are currently marketed, with 18 more in clinical development.

What are the marketed Dopamine agonist drugs?

Marketed Dopamine agonist drugs include Dopamine Agonists, Cabergoline (Dopamine Agonist), DC, combination with dopamine agonist cabergoline, Neupro®, DAM.

Dopamine agonist

7 marketed 16 in Phase 3 2 in Phase 2

This page covers all Dopamine agonist drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Dopamine receptors (D1-D5), Dopamine D2 receptor, dopamine receptor.

Targets

Dopamine receptors (D1-D5) · Dopamine D2 receptor · dopamine receptor · Dopamine receptors (D1, D2, D3, D4, D5) · Dopamine receptor · D2 dopamine receptor, D3 dopamine receptor · Dopamine D2 and D3 receptors · D1 and D2 dopamine receptors · Dopamine receptors (D2, D3) · Dopamine receptors

Marketed (7)

Dopamine Agonists · Leiden University Medical Center · Neurology
Dopamine agonists bind to and activate dopamine receptors in the brain, mimicking the effects of the neurotransmitter dopamine.
Cabergoline (Dopamine Agonist) · University Hospital, Basel, Switzerland · Endocrinology
Cabergoline is a dopamine D2 receptor agonist that inhibits prolactin secretion from the anterior pituitary gland.
DC · Gary Archer Ph.D. · Neurology
DC is a dopamine agonist that acts on dopamine receptors in the brain.
combination with dopamine agonist cabergoline · Ludwig-Maximilians - University of Munich · Endocrinology
Cabergoline is a dopamine agonist that stimulates dopamine D2 receptors to inhibit prolactin secretion from the anterior pituitary gland.
Neupro® · UCB Pharma · Neurology
Neupro is a dopamine agonist that stimulates dopamine receptors in the brain to restore dopamine signaling in patients with Parkinson's disease and restless legs syndrome.
DAM · Beijing Bozhiyin T&S Co., Ltd. · Neurology
DAM is a dopamine agonist that acts on dopamine receptors in the brain.
Pramipexole (Mirapex) · Massachusetts General Hospital · Neurology
Pramipexole is a dopamine agonist that stimulates D2 and D3 dopamine receptors in the brain to restore dopamine signaling.

Phase 3 pipeline (16)

Requip PR · Rajesh Pahwa, MD · Neurology
Requip PR is a dopamine agonist that stimulates dopamine receptors in the brain to increase dopamine activity.
Continuous Subcutaneous Lisuride Infusion · Axxonis Pharma AG · Neurology
Lisuride is a dopamine agonist that activates dopamine receptors to improve motor symptoms and reduce involuntary movements in Parkinson's disease.
Continuous Release Dopamine Agonists · University of Toledo · Neurology
Continuous release dopamine agonists stimulate dopamine receptors in the brain to provide sustained therapeutic effects for movement and neurological disorders.
Continuous Apomorphine infusion · Rennes University Hospital · Neurology
Apomorphine is a dopamine agonist that stimulates dopamine receptors in the brain to improve motor symptoms in Parkinson's disease.
Usual dopaminergic per os treatment · Rennes University Hospital · Neurology
Activates dopaminergic receptors to increase dopamine levels in the brain.
Placebo- Sinemet · Intec Pharma Ltd. · Neurology
Sinemet is a combination of carbidopa and levodopa, which work together to increase dopamine levels in the brain.
injection of placebo of apomorphine · University Hospital, Toulouse · Neurology
Apomorphine is a dopamine agonist that mimics the action of dopamine in the brain.
ropinirole PR/XR · GlaxoSmithKline · Neurology
Ropinirole PR/XR is a dopamine agonist that mimics the action of dopamine in the brain, helping to regulate movement and reduce symptoms of Parkinson's disease.
Ropinirole XL (formerly CR) · GlaxoSmithKline · Neurology
Ropinirole XL is a dopamine agonist that works by stimulating dopamine receptors in the brain.
APL-130277 · Sumitomo Pharma America, Inc. · Neurology
APL-130277 is a subcutaneous apomorphine formulation that acts as a dopamine agonist to provide rapid symptom relief in Parkinson's disease.
pramipexole or ropinirole · Desitin Arzneimittel GmbH · Neurology
Pramipexole and ropinirole are dopamine agonists that activate dopamine receptors in the brain, mimicking the action of dopamine.
injection of apomorphine · University Hospital, Toulouse · Neurology
Apomorphine is a dopamine agonist that stimulates dopamine receptors in the brain to improve motor symptoms in Parkinson's disease.
apomorphine HCl injection · Mylan Bertek Pharmaceuticals · Neurology
Apomorphine HCl injection acts as a dopamine agonist, mimicking the action of dopamine in the brain.
ropinirole IR · GlaxoSmithKline · Neurology
Ropinirole IR works by activating dopamine receptors in the brain, increasing dopamine levels and helping to alleviate symptoms of Parkinson's disease.
ropinirole immediate release · GlaxoSmithKline · Neurology
Ropinirole is a dopamine agonist that works by activating dopamine receptors in the brain.
subcutaneous apomorphine · Sumitomo Pharma America, Inc. · Neurology
Subcutaneous apomorphine is a dopamine agonist that stimulates dopamine receptors in the brain to rapidly relieve motor symptoms of Parkinson's disease.

Phase 2 pipeline (2)

Anti-Parkinson medication · Beth Israel Deaconess Medical Center · Neurology
This drug works by increasing dopamine levels in the brain to alleviate Parkinson's symptoms.
Apomorphine Nasal Powder · Britannia Pharmaceuticals Ltd. · Neurology
Apomorphine works by stimulating dopamine receptors in the brain, which helps to improve motor function in people with Parkinson's disease.