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Apomorphine Nasal Powder

Britannia Pharmaceuticals Ltd. · Phase 2 active Small molecule

Apomorphine works by stimulating dopamine receptors in the brain, which helps to improve motor function in people with Parkinson's disease.

Apomorphine works by stimulating dopamine receptors in the brain, which helps to improve motor function in people with Parkinson's disease. Used for Treatment of 'off' episodes in advanced Parkinson's disease.

At a glance

Generic nameApomorphine Nasal Powder
SponsorBritannia Pharmaceuticals Ltd.
Drug classDopamine agonist
TargetDopamine receptor
ModalitySmall molecule
Therapeutic areaNeurology
PhasePhase 2

Mechanism of action

Apomorphine is a dopamine agonist that directly stimulates dopamine receptors in the brain, bypassing the normal dopamine-producing neurons that are damaged in Parkinson's disease. This helps to improve motor function, including tremors, stiffness, and bradykinesia. Apomorphine is typically used as a rescue medication to help manage 'off' episodes in people with advanced Parkinson's disease.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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