{"id":"apomorphine-nasal-powder","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Dizziness"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Apomorphine is a dopamine agonist that directly stimulates dopamine receptors in the brain, bypassing the normal dopamine-producing neurons that are damaged in Parkinson's disease. This helps to improve motor function, including tremors, stiffness, and bradykinesia. Apomorphine is typically used as a rescue medication to help manage 'off' episodes in people with advanced Parkinson's disease.","oneSentence":"Apomorphine works by stimulating dopamine receptors in the brain, which helps to improve motor function in people with Parkinson's disease.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:28:49.379Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of 'off' episodes in advanced Parkinson's disease"}]},"trialDetails":[{"nctId":"NCT00346827","phase":"PHASE2, PHASE3","title":"Apomorphine Nasal Powder in the Treatment of Parkinson's Disease \"Off\" Periods.","status":"COMPLETED","sponsor":"Britannia Pharmaceuticals Ltd.","startDate":"2006-07","conditions":"Parkinson's Disease","enrollment":36}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Apomorphine Nasal Powder","genericName":"Apomorphine Nasal Powder","companyName":"Britannia Pharmaceuticals Ltd.","companyId":"britannia-pharmaceuticals-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Apomorphine works by stimulating dopamine receptors in the brain, which helps to improve motor function in people with Parkinson's disease. Used for Treatment of 'off' episodes in advanced Parkinson's disease.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}