Tetracycline antibiotic

This page covers all Tetracycline antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial 30S ribosomal subunit, Bacterial 30S ribosome, 72 kDa type IV collagenase, Stromelysin-1, Collagenase 3.

Targets

Bacterial 30S ribosomal subunit · Bacterial 30S ribosome · 72 kDa type IV collagenase, Stromelysin-1, Collagenase 3 · Bacterial 30S ribosomal subunit; matrix metalloproteinases · 30S ribosomal subunit · Bacterial ribosome (30S subunit); also has anti-inflammatory effects on host immune mediators · Bacterial ribosome (30S subunit); also has anti-inflammatory effects on host immune cells

Marketed (19)

• Tetracycline Pill · National Cheng-Kung University Hospital · Infectious Disease
  Tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation.
• Minocycline vs Lymecycline · Darier · Dermatology / Infectious Disease
  Both minocycline and lymecycline are tetracycline antibiotics that inhibit bacterial protein synthesis by binding to the 30S ribosomal subunit.
• Minocycline HCl · OraPharma · Infectious Disease; Dermatology; Periodontal Disease
  Minocycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
• DoxyPEP · Chinese University of Hong Kong · Infectious Disease / Sexual Health
  DoxyPEP is doxycycline used as a post-exposure prophylaxis to prevent sexually transmitted infections by inhibiting bacterial protein synthesis.
• Doxycycline Tablets · Yaounde Central Hospital · Infectious Disease
  Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation and bacterial growth.
• Doxycycline pre-operatively · University of Pittsburgh · Infectious Disease / Surgical Prophylaxis
  Doxycycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, and when used pre-operatively, reduces surgical site infection risk through antimicrobial prophylaxis.
• Minocycline HCl Microspheres · OraPharma · Dentistry / Periodontics
  Minocycline HCl microspheres deliver the antibiotic minocycline directly into periodontal pockets to inhibit bacterial growth and reduce inflammation in periodontal disease.
• Tetracyclin ointment · University of Oslo · Infectious Disease / Dermatology
  Tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation and bacterial growth.
• Vibramycin · Generic (originally Pfizer) · Infectious Disease
• Doxycycline Hyclate Enteric-Coated Capsules · The Third Xiangya Hospital of Central South University · Infectious Disease
  Doxycycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
• Oral doxycycline hyclate · Galderma R&D · Infectious Disease
  Doxycycline hyclate is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
• Minocycline (yes/no) · Medical University of South Carolina · Infectious Disease
  Minocycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
• topical tetracycline · Johns Hopkins University · Dermatology / Infectious Disease
  Topical tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, reducing microbial growth on the skin surface.
• tetracycline (BQ10) · National Taiwan University Hospital · Infectious Disease
  Tetracycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation.
• Tigecycline antimicrobial-lock solution · Clinica Universidad de Navarra, Universidad de Navarra · Infectious Disease
  Tigecycline is a broad-spectrum antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation.
• Amzeeq 4% Topical Foam · Edward Lain, MD · Dermatology
  Amzeeq is a topical foam formulation of minocycline that reduces inflammation and bacterial colonization in acne by inhibiting bacterial protein synthesis and suppressing inflammatory mediators.
• Doxycycline post-exposure prophylaxis · University of Washington · Infectious Disease
  Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing pathogenic bacteria from multiplying after potential exposure.
• Omadacycline Injection · Wake Forest University Health Sciences · Infectious Disease
  Omadacycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the ribosome.
• Usual doses of tigecycline · Air Force Specialized Hospital, Cairo, Egypt · Infectious Disease
  Tigecycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide elongation.

Phase 3 pipeline (8)

• Minocycline hydrochloride capsules · Beijing Tiantan Hospital · Infectious Disease
  Minocycline is a tetracycline antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
• Placebo + Doxycycline · Hospital General de Mexicali · Infectious diseases
  Doxycycline is a broad-spectrum antibiotic that inhibits protein synthesis in bacteria by binding to the 30S ribosomal subunit.
• FMX103 minocycline foam 1.5% · Vyne Therapeutics Inc. · Dermatology
  Minocycline, a tetracycline antibiotic, reduces inflammation and bacterial colonization in acne by inhibiting bacterial protein synthesis and suppressing inflammatory mediators.
• oxytetracycline, taro elixir · Laboratorios Goulart S.A. · Infectious disease
  Oxytetracycline is a broad-spectrum antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.
• intrapleural minocycline instillation · National Taiwan University Hospital · Infectious Disease
  Minocycline has antimicrobial properties that may help reduce inflammation and prevent infection in the pleural space.
• Systemic Doxycycline and Sham aPDT · University of Sao Paulo · Infectious Disease / Periodontal Disease
  Doxycycline is a broad-spectrum tetracycline antibiotic that inhibits bacterial protein synthesis and possesses anti-inflammatory properties; when combined with sham aPDT (antimicrobial photodynamic therapy), it is being evaluated for its potential antimicrobial and immunomodulatory effects.
• FMX-101, 4% minocycline foam · Vyne Therapeutics Inc. · Dermatology
  Minocycline, a tetracycline antibiotic, reduces inflammation and bacterial colonization in acne by inhibiting bacterial protein synthesis and suppressing inflammatory mediators.
• Experimental: doxycycline · ANRS, Emerging Infectious Diseases · Infectious Diseases
  Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing peptide bond formation.

Phase 2 pipeline (2)

• BPX-01 2% Minocycline Topical Gel · BioPharmX, Inc. · Infectious Disease
  Minocycline is a tetracycline antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.
• BPX-01 1% Minocycline Topical Gel · BioPharmX, Inc. · Infectious Disease
  Minocycline is a tetracycline antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.