30S ribosomal subunit — Drug Target

All drugs that target 30S ribosomal subunit — marketed and clinical-stage. Includes 4 drug classes acting on this target.

Drug classes

Tetracycline · Tetracycline-class Antibacterial [EPC] · Aminoglycoside antibiotic · tetracycline antibiotic

Marketed (2)

• CHLORTETRACYCLINE HYDROCHLORIDE · Tetracycline · Infectious Disease
  Chlortetracycline hydrochloride inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA to the ribosome.
• Tygacil · Fresenius Kabi · Tetracycline-class Antibacterial [EPC] · Infectious Disease
  Tygacil works by binding to the 30S ribosomal subunit of bacteria, preventing the aminoacyl-tRNA from binding and thereby inhibiting protein synthesis.

Phase 3 pipeline (3)

• aerosol inhaled Amikacin Sulfate Injection · Shanghai Zhongshan Hospital · Aminoglycoside antibiotic · Infectious disease
  Amikacin Sulfate Injection works by inhibiting bacterial protein synthesis.
• Placebo + Doxycycline · Hospital General de Mexicali · tetracycline antibiotic · Infectious diseases
  Doxycycline is a broad-spectrum antibiotic that inhibits protein synthesis in bacteria by binding to the 30S ribosomal subunit.
• oxytetracycline, taro elixir · Laboratorios Goulart S.A. · tetracycline antibiotic · Infectious disease
  Oxytetracycline is a broad-spectrum antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.

Phase 2 pipeline (3)

• BPX-01 2% Minocycline Topical Gel · BioPharmX, Inc. · tetracycline antibiotic · Infectious Disease
  Minocycline is a tetracycline antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.
• BPX-01 1% Minocycline Topical Gel · BioPharmX, Inc. · tetracycline antibiotic · Infectious Disease
  Minocycline is a tetracycline antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.
• Arbekacin Sulfate · U.S. Army Medical Research and Development Command · Aminoglycoside antibiotic · Infectious Disease
  Aminoglycoside antibiotic that inhibits protein synthesis by binding to the 30S ribosomal subunit.