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intrapleural minocycline instillation
Minocycline has antimicrobial properties that may help reduce inflammation and prevent infection in the pleural space.
Minocycline has antimicrobial properties that may help reduce inflammation and prevent infection in the pleural space. Used for Pleural infection or empyema.
At a glance
| Generic name | intrapleural minocycline instillation |
|---|---|
| Sponsor | National Taiwan University Hospital |
| Drug class | tetracycline antibiotic |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
Minocycline, a tetracycline antibiotic, has been shown to have anti-inflammatory effects in addition to its antimicrobial properties. By instilling minocycline into the pleural space, it may help reduce the risk of infection and inflammation in patients with pleural diseases.
Approved indications
- Pleural infection or empyema
Common side effects
- Nausea
- Vomiting
- Diarrhea
Key clinical trials
- Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax (PHASE3)
- Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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