Platinum-based chemotherapy
This page covers all Platinum-based chemotherapy drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting DNA, Thymidylate synthase, topoisomerase I, DNA replication machinery.
Targets
DNA · Thymidylate synthase, topoisomerase I · DNA replication machinery
Phase 3 pipeline (22)
- oxaliplatin;s1 · Chinese Academy of Medical Sciences · Oncology
Oxaliplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription. - oxaliplatin, folinic acid, fluorouracil · GERCOR - Multidisciplinary Oncology Cooperative Group · Oncology
Oxaliplatin works by interfering with DNA replication in cancer cells, causing cell death. - oxaliplatin, irinotecan, folinic acid, fluorouracil · GERCOR - Multidisciplinary Oncology Cooperative Group · Oncology
Oxaliplatin, irinotecan, folinic acid, and fluorouracil work together to inhibit thymidylate synthase and DNA synthesis, leading to cell death in rapidly dividing cancer cells. - RT+CDDP/5-FU · Associazione Volontari Pazienti Oncologici · Oncology
RT+CDDP/5-FU is a combination chemotherapy regimen that works by inhibiting DNA replication and interfering with DNA repair, ultimately leading to cell death. - SOX or CAPOX regimen · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Oncology
Oxaliplatin and capecitabine work by interfering with DNA replication and repair, thereby inhibiting cancer cell growth. - Weekly cisplatin with RT · Korea Cancer Center Hospital · Oncology
Cisplatin works by crosslinking DNA, thereby inhibiting DNA replication and transcription. - concomitant cisplatin · Groupe Oncologie Radiotherapie Tete et Cou · Oncology
Cisplatin works by interfering with DNA replication, causing cell death in rapidly dividing cancer cells. - chemoradiotherapy Cisplatin · Shandong Cancer Hospital and Institute · Oncology
Cisplatin works by interfering with DNA replication, causing cell death in rapidly dividing cancer cells. - placebo, carboplatin, etoposide，or Topotecan · Jiangsu Simcere Pharmaceutical Co., Ltd. · Oncology
Carboplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription. - mFOLFOX6 or CAPOX · LI XIN-XIANG · Oncology
mFOLFOX6 or CAPOX is a chemotherapy regimen that combines oxaliplatin, 5-fluorouracil, and leucovorin to target rapidly dividing cancer cells. - carboplatin (Cb) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Oncology
Carboplatin works by forming platinum-DNA adducts, which interfere with DNA replication and transcription, ultimately leading to cell death. - concurrent chemotherapy with cisplatin · Air Force Military Medical University, China · Oncology
Cisplatin works by interfering with DNA replication, causing cell death in rapidly dividing cancer cells. - liposomal cisplatin · Federation Francophone de Cancerologie Digestive · Oncology
Liposomal cisplatin works by releasing cisplatin, a platinum-based chemotherapy drug, in a targeted manner to kill cancer cells. - Oxaliplatin for injection · Shanghai Junshi Bioscience Co., Ltd. · Oncology
Oxaliplatin works by interfering with DNA replication in cancer cells, leading to cell death. - Perioperative FOLFOX · Sixth Affiliated Hospital, Sun Yat-sen University · Oncology
FOLFOX is a chemotherapy regimen that combines oxaliplatin, 5-fluorouracil, and leucovorin to kill rapidly dividing cancer cells. - mFOLFOX6 adjuvant chemotherapy · Sun Yat-sen University · Oncology
mFOLFOX6 is a combination chemotherapy regimen that targets rapidly dividing cancer cells. - Oxaliplatin(Aiheng) · The First Affiliated Hospital of Henan University of Science and Technology · Oncology
Oxaliplatin works by interfering with DNA replication in cancer cells, leading to cell death. - SHR-1316; Carboplatin; Etoposide；Radiotherapy · Jiangsu HengRui Medicine Co., Ltd. · Oncology
Carboplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting cancer cell growth and inducing apoptosis. - oxaliplatin+Leucovorin+5-FU · Xu jianmin · Oncology
Oxaliplatin works by interfering with DNA replication in cancer cells, while 5-FU is a thymidylate synthase inhibitor that disrupts DNA synthesis, and Leucovorin is a folate analog that helps stabilize 5-FU. - mFOLFOXIRI adjuvant chemotherapy · Sun Yat-sen University · Oncology
mFOLFOXIRI is a combination chemotherapy regimen that targets rapidly dividing cancer cells. - XELOX intensive treatment group · Zhejiang Cancer Hospital · Oncology
Oxaliplatin works by damaging the DNA of cancer cells, preventing them from reproducing. - lobaplatin , 5-FU ,leucovorin · Taian Cancer Hospital · Oncology
Lobaplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription.
Phase 2 pipeline (18)
- FOLFOX induction regimen · Hoffmann-La Roche · Oncology
Oxaliplatin inhibits DNA replication by binding to DNA and inducing DNA damage. - Carboplatin AUC7 · Centre Leon Berard · Oncology
Carboplatin works by interfering with DNA replication in cancer cells, leading to cell death. - Drug: carboplatin · AstraZeneca · Oncology
Alkylating agent that forms platinum-DNA adducts, inhibiting DNA replication and transcription. - Any platinum-based doublet chemotherapy · Eli Lilly and Company · Oncology
Platinum-based doublet chemotherapy works by interfering with DNA replication in cancer cells, ultimately leading to cell death. - Platinum Compound · SWOG Cancer Research Network · Oncology
Platinum-based chemotherapy agent that binds to DNA, inhibiting cancer cell replication - GEMOX · Jiangsu HengRui Medicine Co., Ltd. · Oncology
Gemcitabine and oxaliplatin combination chemotherapy - CDDP 75 · Holy Name Medical Center, Inc. · Oncology
CDDP 75 is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription. - Carboplatin AUC 5 · CatalYm GmbH · Oncology
Alkylating agent that interferes with DNA replication - CDDP 50 · Holy Name Medical Center, Inc. · Oncology
CDDP 50 is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting DNA replication and transcription. - Consolidation Carboplatin · Radiation Therapy Oncology Group · Oncology
Carboplatin works by interfering with DNA replication in cancer cells, leading to cell death. - Cisplatin Combined With Topotecan · Chinese Anti-Cancer Association · Oncology
Cisplatin works by crosslinking DNA, thereby inhibiting DNA replication and transcription, while topotecan inhibits topoisomerase I, preventing DNA repair and replication. - FOLFIRINOX chemotherapy · OncoSil Medical Limited · Oncology
FOLFIRINOX is a chemotherapy regimen that combines four different drugs to target rapidly dividing cancer cells. - Carboplatin i.d. Days 1 & 15 · Windy Hill Medical, Inc. · Oncology
Carboplatin is a platinum-based chemotherapy drug that works by crosslinking DNA, thereby inhibiting cancer cell replication. - Carboplatin AUC-10 · Barts & The London NHS Trust · Oncology
Alkylating agent that forms platinum-DNA adducts, inhibiting DNA replication and transcription. - CarboP-pacliT · Centre Oscar Lambret · Oncology
CarboP-pacliT is a chemotherapy medication that works by interfering with DNA replication in cancer cells. - Carboplatin-based chemotherapy · Hoffmann-La Roche · Oncology
Platinum-based DNA alkylating agent - DDP synchronous with radiotherapy · Yong Zhang,MD · Oncology
DDP is a chemotherapy drug that works by interfering with DNA replication, making it difficult for cancer cells to divide and grow. - Carboplatin AUC2 · Merck Sharp & Dohme LLC · Oncology
Alkylating agent that forms platinum-DNA adducts, inhibiting DNA replication and transcription.