Who are Listerine Total Care Zero's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Stabilized chlorine dioxide oral rinse, Chlorhexidine Digluconate Mouthwash without Alcohol, Chlorhexidine rinse, Chlorhexidine 0.06% mouthrinse, Chlorhexidine mouthwash (0.2%).

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Listerine Total Care Zero — Competitive Intelligence Brief

Listerine Total Care Zero (Listerine Total Care Zero) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimicrobial oral rinse. Area: Oral Health / Dentistry.

marketed Antimicrobial oral rinse Oral Health / Dentistry Small molecule Live · refreshed every 30 min

Target snapshot

Listerine Total Care Zero (Listerine Total Care Zero) — Johnson & Johnson Consumer Inc. (J&JCI). Listerine Total Care Zero is an antimicrobial oral rinse that kills bacteria and reduces plaque and gingivitis without alcohol.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Listerine Total Care Zero TARGET	Listerine Total Care Zero	Johnson & Johnson Consumer Inc. (J&JCI)	marketed	Antimicrobial oral rinse
Stabilized chlorine dioxide oral rinse	Stabilized chlorine dioxide oral rinse	Rowpar Pharmaceuticals, Inc.	marketed	Antimicrobial oral rinse
Chlorhexidine Digluconate Mouthwash without Alcohol	Chlorhexidine Digluconate Mouthwash without Alcohol	GlaxoSmithKline	marketed	Antimicrobial oral rinse
Chlorhexidine rinse	Chlorhexidine rinse	Universidade Estadual Paulista Júlio de Mesquita Filho	marketed	Antimicrobial oral rinse	Bacterial cell membrane and proteins
Chlorhexidine 0.06% mouthrinse	Chlorhexidine 0.06% mouthrinse	University of Oslo	marketed	Antimicrobial oral rinse	Bacterial cell membrane and proteins
Chlorhexidine mouthwash (0.2%)	Chlorhexidine mouthwash (0.2%)	Al-Mustansiriyah University	phase 3	Antimicrobial oral rinse / Antiseptic	Bacterial cell membrane

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimicrobial oral rinse class)

GlaxoSmithKline · 1 drug in this class
Johnson & Johnson Consumer Inc. (J&JCI) · 1 drug in this class
Rowpar Pharmaceuticals, Inc. · 1 drug in this class
Universidade Estadual Paulista Júlio de Mesquita Filho · 1 drug in this class
University of Oslo · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Listerine Total Care Zero — Competitive Intelligence Brief. https://druglandscape.com/ci/listerine-total-care-zero. Accessed 2026-05-16.

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