Lidocaine patch 1.8% — Competitive Intelligence Brief

Lidocaine patch 1.8% (Lidocaine patch 1.8%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Pain management.

marketed Local anesthetic Voltage-gated sodium channels Pain management Small molecule

Target snapshot

Lidocaine patch 1.8% (Lidocaine patch 1.8%) — Scilex Pharmaceuticals, Inc.. Lidocaine blocks sodium channels in nerve fibers, interrupting pain signal transmission at the site of application.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Lidocaine patch 1.8% TARGET	Lidocaine patch 1.8%	Scilex Pharmaceuticals, Inc.	marketed	Local anesthetic	Voltage-gated sodium channels
Prilocaine 2.5%	Prilocaine 2.5%	Express Specialty Pharmacy	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Dyclonine hydrochloride mucilage	Dyclonine hydrochloride mucilage	Peking Union Medical College Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine 0.25% with Epinephrine	Bupivacaine 0.25% with Epinephrine	Holy Cross Hospital, Florida	marketed	Local anesthetic with vasopressor	Voltage-gated sodium channels
Bupivacaine + Sufentanil epidural	Bupivacaine + Sufentanil epidural	Charles University, Czech Republic	marketed	Local anesthetic + opioid combination	Voltage-gated sodium channels (bupivacaine); mu opioid receptor (sufentanil)
guided injection of mepivacaine	guided injection of mepivacaine	Complejo Hospitalario Universitario de Granada	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Bupivacaine with intrathecal morphine	Bupivacaine with intrathecal morphine	Centre Hospitalier Universitaire Vaudois	marketed	Local anesthetic with intrathecal opioid	Voltage-gated sodium channels (bupivacaine); mu-opioid receptors (morphine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class