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guided injection of mepivacaine
guided injection of mepivacaine is a Local anesthetic (amide) Small molecule drug developed by Complejo Hospitalario Universitario de Granada. It is currently FDA-approved for Local anesthesia via guided injection for regional nerve blocks and infiltration anesthesia. Also known as: guided perineural injection.
Mepivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission.
Mepivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission. Used for Local anesthesia via guided injection for regional nerve blocks and infiltration anesthesia.
At a glance
| Generic name | guided injection of mepivacaine |
|---|---|
| Also known as | guided perineural injection |
| Sponsor | Complejo Hospitalario Universitario de Granada |
| Drug class | Local anesthetic (amide) |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia / Pain Management |
| Phase | FDA-approved |
Mechanism of action
Mepivacaine is an amide-type local anesthetic that reversibly inhibits sodium influx into nerve fibers, thereby preventing depolarization and conduction of action potentials. When administered via guided injection (likely ultrasound or fluoroscopy-guided), it achieves targeted anesthesia at specific anatomical sites. The guided delivery approach enhances precision and efficacy while potentially reducing systemic exposure.
Approved indications
- Local anesthesia via guided injection for regional nerve blocks and infiltration anesthesia
Common side effects
- Injection site reactions (pain, erythema)
- Transient paresthesia
- Systemic toxicity (if absorbed in excess)
- Allergic reactions (rare with amides)
Key clinical trials
- PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach (NA)
- Platelet-Rich Plasma Versus Home-Based Exercise for Partial-Thickness Supraspinatus Tears (NA)
- Stellate Ganglion Block for COVID-induced Parosmia (PHASE2)
- Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty (PHASE4)
- Therapeutic Effect of Shoulder Anterior Capsular Block Versus Suprascapular Nerve Block in Patients With Frozen Shoulder (NA)
- Comparison of Ultrasound-guided Electrolysis Therapy vs. Sham Electrolysis in Patients With Patellar Tendinopathy: A Prospective Randomized Study Including MRI and Shear-wave Ultrasound Elastography Imaging (NA)
- Comparing General Anesthesia With Single Injection Peribulbar Block With 3 Different Drugs (NA)
- Effectiveness of Non-surgical Management in Rotator Cuff Calcific Tendinopathy (THE EFFECT TRIAL) (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- guided injection of mepivacaine CI brief — competitive landscape report
- guided injection of mepivacaine updates RSS · CI watch RSS
- Complejo Hospitalario Universitario de Granada portfolio CI
Frequently asked questions about guided injection of mepivacaine
What is guided injection of mepivacaine?
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Is guided injection of mepivacaine also known as anything else?
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Related
- Drug class: All Local anesthetic (amide) drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Complejo Hospitalario Universitario de Granada — full pipeline
- Therapeutic area: All drugs in Anesthesia / Pain Management
- Indication: Drugs for Local anesthesia via guided injection for regional nerve blocks and infiltration anesthesia
- Also known as: guided perineural injection
- Compare: guided injection of mepivacaine vs similar drugs
- Pricing: guided injection of mepivacaine cost, discount & access