Isoflurane, Sevoflurane or Desflurane — Competitive Intelligence Brief

Isoflurane, Sevoflurane or Desflurane (Isoflurane, Sevoflurane or Desflurane) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Volatile anesthetic. Area: Anesthesiology.

marketed Volatile anesthetic GABA-A receptor, NMDA receptor Anesthesiology Small molecule

Target snapshot

Isoflurane, Sevoflurane or Desflurane (Isoflurane, Sevoflurane or Desflurane) — King's College Hospital NHS Trust. These volatile anesthetics enhance inhibitory GABA receptor signaling and inhibit excitatory NMDA receptor function to produce general anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Isoflurane, Sevoflurane or Desflurane TARGET	Isoflurane, Sevoflurane or Desflurane	King's College Hospital NHS Trust	marketed	Volatile anesthetic	GABA-A receptor, NMDA receptor
original sevoflurane	original sevoflurane	Asan Medical Center	marketed	Volatile anesthetic	GABA-A receptor, NMDA receptor
sevoflurane in step up concentration	sevoflurane in step up concentration	University Hospital, Ghent	marketed	Volatile general anesthetic	GABA-A receptor, NMDA receptor
Suprane (desflurane), Baxter	Suprane (desflurane), Baxter	Medical University of Gdansk	marketed	Volatile anesthetic	GABA-A receptor, NMDA receptor
Sevoflurane/Ultane	Sevoflurane/Ultane	Kaohsiung Medical University Chung-Ho Memorial Hospital	marketed	Volatile general anesthetic	GABA-A receptor, NMDA receptor
Isoflurane Volatile Liquid	Isoflurane Volatile Liquid	Federal University of São Paulo	marketed	Volatile anesthetic	GABA-A receptor, NMDA receptor
Sevoflurane Inhalation Liquid	Sevoflurane Inhalation Liquid	Damanhour Teaching Hospital	marketed	Volatile general anesthetic	GABA-A receptor, NMDA receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Volatile anesthetic class)

1. Medical University of Gdansk · 2 drugs in this class
2. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
3. Federal University of São Paulo · 1 drug in this class
4. King's College Hospital NHS Trust · 1 drug in this class
5. London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · 1 drug in this class
6. The Cleveland Clinic · 1 drug in this class
7. University Hospital, Basel, Switzerland · 1 drug in this class
8. Asan Medical Center · 1 drug in this class
9. University Hospital, Clermont-Ferrand · 1 drug in this class