Intra-articular Lidocaine — Competitive Intelligence Brief

Intra-articular Lidocaine (Intra-articular Lidocaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Pain management / Orthopedics.

marketed Local anesthetic Voltage-gated sodium channels Pain management / Orthopedics Small molecule

Target snapshot

Intra-articular Lidocaine (Intra-articular Lidocaine) — University of Central Florida. Lidocaine blocks sodium channels in nerve fibers to provide local anesthesia and pain relief when injected directly into the joint space.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Intra-articular Lidocaine TARGET	Intra-articular Lidocaine	University of Central Florida	marketed	Local anesthetic	Voltage-gated sodium channels
Infiltration - EXPAREL	Infiltration - EXPAREL	Pacira Pharmaceuticals, Inc	marketed	Long-acting local anesthetic	Voltage-gated sodium channels
Anesthetics, Local	Anesthetics, Local	University of Alberta	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine and Fentanyl	Levobupivacaine and Fentanyl	Hamad Medical Corporation	marketed	Local anesthetic with opioid analgesic combination	Voltage-gated sodium channels; mu-opioid receptor
Lidocaine 2% Injectable Solution	Lidocaine 2% Injectable Solution	Erasme University Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine 2% Jelly	Lidocaine 2% Jelly	Hermann Eye Center	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine plus adrenaline	Lidocaine plus adrenaline	University of Santiago de Compostela	marketed	Local anesthetic with vasopressor	Voltage-gated sodium channels; alpha-1 and beta-1 adrenergic receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class