ChloraPrep Hi-Lite Orange — Competitive Intelligence Brief

ChloraPrep Hi-Lite Orange (ChloraPrep Hi-Lite Orange) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical antiseptic. Area: Surgical prophylaxis / Infection prevention.

phase 3 Topical antiseptic Bacterial cell membrane and proteins Surgical prophylaxis / Infection prevention Small molecule

Target snapshot

ChloraPrep Hi-Lite Orange (ChloraPrep Hi-Lite Orange) — Solventum US LLC. ChloraPrep Hi-Lite Orange is a chlorhexidine-based antiseptic skin preparation that kills microorganisms on the skin surface to prevent surgical site infections.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
ChloraPrep Hi-Lite Orange TARGET	ChloraPrep Hi-Lite Orange	Solventum US LLC	phase 3	Topical antiseptic	Bacterial cell membrane and proteins
Chlorhexidine 0.2% Mouthrinse	Chlorhexidine 0.2% Mouthrinse	University of Oslo	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
A (Chloraprep)	A (Chloraprep)	Instituto de Investigacion Sanitaria La Fe	marketed	Topical antiseptic	Bacterial cell membrane and proteins
Chlorhexidine rinse	Chlorhexidine rinse	Universidade Estadual Paulista Júlio de Mesquita Filho	marketed	Antimicrobial oral rinse	Bacterial cell membrane and proteins
Adapalene + benzoyl peroxide samples	Adapalene + benzoyl peroxide samples	Wake Forest University	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Chlorhexidine oral care	Chlorhexidine oral care	University of Pavia	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Derm Research, PLLC	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical antiseptic class)

1. Poitiers University Hospital · 2 drugs in this class
2. Professional Disposables International, Inc. · 2 drugs in this class
3. Central DuPage Hospital · 2 drugs in this class
4. Solventum US LLC · 1 drug in this class
5. University of British Columbia · 1 drug in this class
6. University of Iowa · 1 drug in this class
7. C. R. Bard · 1 drug in this class
8. Zurex Pharma, Inc. · 1 drug in this class
9. Instituto de Investigacion Sanitaria La Fe · 1 drug in this class
10. Johnson & Johnson Consumer Inc. (J&JCI) · 1 drug in this class