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Adapalene + benzoyl peroxide samples
Adapalene is a retinoid that normalizes skin cell turnover and reduces inflammation, while benzoyl peroxide kills acne-causing bacteria and provides additional antimicrobial activity.
Adapalene is a retinoid that normalizes skin cell turnover and reduces inflammation, while benzoyl peroxide kills acne-causing bacteria and provides additional antimicrobial activity. Used for Acne vulgaris.
At a glance
| Generic name | Adapalene + benzoyl peroxide samples |
|---|---|
| Also known as | Epiduo |
| Sponsor | Wake Forest University |
| Drug class | Retinoid + peroxide combination |
| Target | Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide) |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Adapalene binds to retinoic acid receptors to regulate keratinocyte differentiation and reduce comedone formation. Benzoyl peroxide acts as an oxidizing agent that generates reactive oxygen species to eliminate Cutibacterium acnes (formerly Propionibacterium acnes) and reduce bacterial resistance. The combination provides complementary mechanisms targeting both inflammatory and comedonal acne.
Approved indications
- Acne vulgaris
Common side effects
- Erythema
- Scaling/peeling
- Dryness
- Irritation
- Photosensitivity
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Adapalene + benzoyl peroxide samples CI brief — competitive landscape report
- Adapalene + benzoyl peroxide samples updates RSS · CI watch RSS
- Wake Forest University portfolio CI