Vitamin D analog

This page covers all Vitamin D analog drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Vitamin D receptor (VDR), Vitamin D receptor.

Targets

Vitamin D receptor (VDR) · Vitamin D receptor

Marketed (8)

• doxercalciferol capsules, Hectorol® capsules · Genzyme, a Sanofi Company · Endocrinology / Nephrology
  Doxercalciferol is a vitamin D analog that activates the vitamin D receptor to regulate calcium and phosphate metabolism and suppress parathyroid hormone secretion.
• Alfarol 1.0 µg · Eli Lilly and Company · Endocrinology / Metabolic disorders
  Alfarol is an active vitamin D analog that binds to the vitamin D receptor to regulate calcium and phosphate homeostasis.
• doxercalciferol capsules, Hectorol® · Genzyme, a Sanofi Company · Endocrinology / Nephrology
  Doxercalciferol is a vitamin D analog that activates the vitamin D receptor to regulate calcium and phosphate metabolism and suppress parathyroid hormone (PTH) secretion.
• Calcifediol Oral Product · OPKO Health, Inc. · Endocrinology / Nephrology
  Calcifediol is an active vitamin D metabolite that binds to the vitamin D receptor to regulate calcium and phosphate homeostasis and modulate immune function.
• Calcitriol (Rocaltrol®) · Joslin Diabetes Center · Endocrinology
  Calcitriol is the active form of vitamin D that binds to vitamin D receptors to regulate calcium and phosphate homeostasis and promote bone mineralization.
• Eldecalcitol capsules · Shanghai Jiao Tong University Affiliated Sixth People's Hospital · Endocrinology / Bone metabolism
  Eldecalcitol is an active vitamin D analog that binds to the vitamin D receptor to regulate calcium and phosphate metabolism and promote bone mineralization.
• Hidroferol® · Hospital Universitario de Canarias · Endocrinology / Metabolic disorders
  Hidroferol is a vitamin D analog that activates vitamin D receptors to regulate calcium and phosphate metabolism and modulate immune function.
• Calcifediol (Vitamin D) · Maimónides Biomedical Research Institute of Córdoba · Endocrinology / Bone and Mineral Metabolism
  Calcifediol is an active form of vitamin D that binds to the vitamin D receptor to regulate calcium and phosphate homeostasis and modulate immune function.

Phase 3 pipeline (10)

• high level Vitamin D · National Cancer Institute, Naples · Oncology
  High level Vitamin D works by regulating calcium and phosphate metabolism in the body.
• normal level Vitamin D · National Cancer Institute, Naples · Osteoporosis
  Vitamin D is essential for maintaining normal levels of calcium and phosphate in the body, which is crucial for bone health.
• Tacalcitol ointment · LEO Pharma · Dermatology
  Tacalcitol ointment is a synthetic vitamin D3 analog that modulates the vitamin D receptor.
• VIT-45 · American Regent, Inc. · Immunology
  VIT-45 is a vitamin D analog that enhances immune function and reduces inflammation through vitamin D receptor signaling.
• Vitamin D oily capsules · University Hospital, Basel, Switzerland · Osteoporosis, Rickets
  Vitamin D capsules work by regulating calcium levels in the body.
• CTAP101 Capsules · OPKO Health, Inc. · Nephrology / Endocrinology
  CTAP101 is a capsule formulation of calcitriol (active vitamin D) that enhances calcium absorption and regulates calcium-phosphate metabolism.
• active vitamin D · Kyowa Kirin, Inc. · Endocrinology
  Active vitamin D works by binding to vitamin D receptors in the body, which helps regulate calcium levels and bone health.
• Vitamin D 2 · Department of Medical Services Ministry of Public Health of Thailand · Endocrinology
  Vitamin D 2 is a form of vitamin D that plays a crucial role in calcium absorption and bone health.
• Vitamin D3 (Low dose) · Shiraz University of Medical Sciences · Endocrinology, Nephrology, Rheumatology
  Vitamin D3 is a fat-soluble vitamin that plays a crucial role in maintaining strong bones, immune function, and overall health.
• Vitamin D3 800 UI/day then 800 UI/day · St. Justine's Hospital · Endocrinology
  Vitamin D3 plays a crucial role in maintaining calcium and phosphate homeostasis, which is essential for bone health.

Phase 2 pipeline (1)

• Dovonex® cream · LEO Pharma · Dermatology
  Calcitriol binds to vitamin D receptors (VDRs) on keratinocytes, promoting differentiation and reducing inflammation.