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active vitamin D
Active vitamin D works by binding to vitamin D receptors in the body, which helps regulate calcium levels and bone health.
Active vitamin D works by binding to vitamin D receptors in the body, which helps regulate calcium levels and bone health. Used for Treatment of hypocalcemia in patients with vitamin D deficiency or insufficiency.
At a glance
| Generic name | active vitamin D |
|---|---|
| Also known as | Oral medicine |
| Sponsor | Kyowa Kirin, Inc. |
| Drug class | Vitamin D analog |
| Target | Vitamin D receptor |
| Modality | Small molecule |
| Therapeutic area | Endocrinology |
| Phase | Phase 3 |
Mechanism of action
Active vitamin D, also known as calcitriol, is the biologically active form of vitamin D. It plays a crucial role in maintaining calcium and phosphate homeostasis, which is essential for bone health. By binding to vitamin D receptors, active vitamin D helps regulate the expression of genes involved in calcium absorption and bone mineralization.
Approved indications
- Treatment of hypocalcemia in patients with vitamin D deficiency or insufficiency
Common side effects
- Hypercalcemia
Key clinical trials
- PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery" (NA)
- Effect of Vitamin D and Folic Acid on Mild Cognitive Impairment (NA)
- Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood (PHASE1)
- Effect of Local Use of Vitamin D on the Rate of Canine Distillization: a Split Mouth Randomized Control Trial (PHASE1)
- Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease (NA)
- Effects of Vitamin D and Calcium on Hyperglycemia and Dyslipidemia in Patients Gestational Diabetes (NA)
- Curcumin, Vitamin D and Green Tea in IBS-D (NA)
- Structured Review: To Optimise Management and Prevent Harm in COPD (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- active vitamin D CI brief — competitive landscape report
- active vitamin D updates RSS · CI watch RSS
- Kyowa Kirin, Inc. portfolio CI