Nitrate vasodilator

This page covers all Nitrate vasodilator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Soluble guanylate cyclase (via nitric oxide), Guanylate cyclase (via nitric oxide).

Targets

Soluble guanylate cyclase (via nitric oxide) · Guanylate cyclase (via nitric oxide)

Marketed (11)

• iso- 5 - mononitrate · Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · Cardiovascular
  Isosorbide 5-mononitrate is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and improve blood flow.
• iso sorbide dinitrate iv bolus or s/l · Soroka University Medical Center · Cardiovascular
  Isosorbide dinitrate is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and reduce cardiac preload and afterload.
• Nitroglycerin (NTG) · Bristol-Myers Squibb · Cardiovascular
  Nitroglycerin is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and dilate blood vessels, reducing cardiac preload and afterload.
• Nitroglycerin infusion · Tri-Service General Hospital · Cardiovascular
  Nitroglycerin is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and dilate blood vessels.
• Monoket Pill · Ohio State University · Cardiovascular
  Monoket is an isosorbide mononitrate that releases nitric oxide to dilate blood vessels and reduce cardiac workload in angina.
• Topical Nitroglycerine · Aultman Health Foundation · Cardiovascular; Dermatology; Wound care
  Topical nitroglycerin releases nitric oxide, which relaxes vascular smooth muscle and improves blood flow to the affected area.
• ISDN ointment · Onze Lieve Vrouwe Gasthuis · Cardiovascular
  ISDN (isosorbide dinitrate) is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and improve blood flow.
• Nitroglycerin patch · GF Strong Rehabilitation Centre · Cardiovascular
  Nitroglycerin is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and dilate blood vessels.
• Glyceryl trinitrate 0.2 · Recep Tayyip Erdogan University · Cardiovascular
  Glyceryl trinitrate is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and improve blood flow.
• Nitro-Bid 2 % Topical Ointment · University of Virginia · Cardiovascular
  Nitroglycerine is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and improve blood flow.
• intravenous nitroglycerin · University of California, San Francisco · Cardiovascular
  Intravenous nitroglycerin is a nitrate vasodilator that releases nitric oxide to relax vascular smooth muscle and reduce preload and afterload on the heart.

Phase 3 pipeline (2)

• Topical organogel with nitroglycerin · MediQuest Therapeutics · Cardiovascular
  Nitroglycerin releases nitric oxide to dilate blood vessels and improve blood flow when applied topically as an organogel formulation.
• Nitroglycerin II · Instituto de Cardiologia de Santa Catarina · Cardiovascular
  Nitroglycerin releases nitric oxide, which activates guanylate cyclase to increase cGMP levels, causing vasodilation of blood vessels.