What are Local anesthetic with corticosteroid adjuvant drugs?

Local anesthetic with corticosteroid adjuvant drugs are pharmacologic agents that share a common mechanism (typically targeting Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)). 4 are currently marketed, with 2 more in clinical development.

What are the marketed Local anesthetic with corticosteroid adjuvant drugs?

Marketed Local anesthetic with corticosteroid adjuvant drugs include Bupivacaine and Dexamethasone Injection, Ropivacaine + dexamethasone, Bupivacaine 0.5% , Dexamethasone, Bupivacaine Hydrochloride combined with dexamethasone.

Local anesthetic with corticosteroid adjuvant

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

4 marketed 2 in Phase 3

This page covers all Local anesthetic with corticosteroid adjuvant drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone), Voltage-gated sodium channels; glucocorticoid receptor, Voltage-gated sodium channels (ropivacaine); glucocorticoid receptor (dexamethasone).

Targets

Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone) · Voltage-gated sodium channels; glucocorticoid receptor · Voltage-gated sodium channels (ropivacaine); glucocorticoid receptor (dexamethasone)

Marketed (4)

Bupivacaine and Dexamethasone Injection · Colette Curtis MD · Pain Management / Regional Anesthesia
Bupivacaine provides local anesthesia by blocking sodium channels in nerve fibers, while dexamethasone reduces inflammation and swelling at the injection site.
Ropivacaine + dexamethasone · Sahiwal medical college sahiwal · Anesthesia / Pain Management
Ropivacaine blocks sodium channels to provide local anesthesia, while dexamethasone reduces inflammation and prolongs the duration of anesthetic effect.
Bupivacaine 0.5% , Dexamethasone · Sisli Hamidiye Etfal Training and Research Hospital · Anesthesia and Pain Management
Bupivacaine blocks sodium channels to provide local anesthesia, while dexamethasone reduces inflammation and swelling at the injection site.
Bupivacaine Hydrochloride combined with dexamethasone · Zhejiang Cancer Hospital · Anesthesia/Pain Management
Bupivacaine provides local anesthesia by blocking sodium channels in nerve fibers, while dexamethasone reduces inflammation and edema at the injection site.

Phase 3 pipeline (2)

Ropivacaine 0.2% + Dexamethasone · Instituto do Coracao · Anesthesia / Pain Management
Ropivacaine blocks sodium channels to provide local anesthesia, while dexamethasone reduces inflammation and edema at the injection site.
Ropivacaine and dexamethasone · University of Texas Southwestern Medical Center · Anesthesia/Pain Management
Ropivacaine provides local anesthesia by blocking sodium channels in nerve fibers, while dexamethasone reduces inflammation and prolongs the duration of the anesthetic effect.

Patent intelligence

local anesthetic with corticosteroid adjuvant patent landscape — aggregated cliff calendar, attackable patents, originator estates