What are Insecticide combination drugs?

Insecticide combination drugs are pharmacologic agents that share a common mechanism (typically targeting Nicotinic acetylcholine receptors; GABA-gated chloride channels). 3 are currently marketed, with 6 more in clinical development.

What are the marketed Insecticide combination drugs?

Marketed Insecticide combination drugs include synergistic combination of insecticides, Spinosad Topical, Permethrin Cream, 5%.

Insecticide combination

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

3 marketed 6 in Phase 3

This page covers all Insecticide combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Nicotinic acetylcholine receptors; GABA-gated chloride channels, Voltage-gated sodium channels (arthropod nervous system), Voltage-gated sodium channels.

Targets

Nicotinic acetylcholine receptors; GABA-gated chloride channels · Voltage-gated sodium channels (arthropod nervous system) · Voltage-gated sodium channels · Acetylcholinesterase · Nicotinic acetylcholine receptor

Marketed (3)

synergistic combination of insecticides · Université de Lubumbashi · Parasitology/Vector Control
A synergistic combination of insecticides that work together to enhance pest control efficacy through complementary modes of action.
Spinosad Topical · Cipher Pharmaceuticals Inc. · Dermatology
Spinosad is a natural insecticide that activates nicotinic acetylcholine receptors and GABA-gated chloride channels in insects, causing paralysis and death.
Permethrin Cream, 5% · Mayne Pharma International Pty Ltd · Dermatology / Parasitology
Permethrin is a synthetic pyrethroid insecticide that disrupts sodium channel function in the nervous system of parasitic arthropods, causing paralysis and death.

Phase 3 pipeline (6)

Permethrin 10 % Creme · Infectopharm Arzneimittel GmbH · Dermatology / Parasitology
Permethrin is a synthetic pyrethroid insecticide that disrupts sodium channel function in the nervous system of parasitic arthropods, causing paralysis and death.
Elimite™ Cream (permethrin) 5% · Encube Ethicals Pvt. Ltd. · Dermatology / Parasitology
Permethrin is a synthetic pyrethroid insecticide that disrupts sodium channel function in the nervous system of parasites, causing paralysis and death.
Malathion Shampoo 0.5% · London School of Hygiene and Tropical Medicine · Parasitology / Dermatology
Malathion is an organophosphate insecticide that inhibits acetylcholinesterase in parasitic arthropods, causing paralysis and death.
spinosad topical suspension, 0.9% · ParaPRO LLC · Entomology
Spinosad topical suspension works by activating nicotinic acetylcholine receptors in the insect nervous system, ultimately leading to the death of the insect.
Ovide (malathion) lotion 0.05% · Sun Pharmaceutical Industries, Inc. · Dermatology
Ovide (malathion) lotion works by killing lice and their eggs on the scalp.
Malathion gel 0.5% · Sun Pharmaceutical Industries, Inc. · Dermatology / Parasitology
Malathion is an organophosphate insecticide that inhibits acetylcholinesterase, causing accumulation of acetylcholine and paralysis of parasites.

Patent intelligence

insecticide patent landscape — aggregated cliff calendar, attackable patents, originator estates