Electrolyte supplement / anticonvulsant / bronchodilator

This page covers all Electrolyte supplement / anticonvulsant / bronchodilator drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting NMDA receptor, voltage-gated calcium channels, NMDA receptor antagonist; calcium channel blocker, Voltage-gated calcium channels, NMDA receptor.

Targets

NMDA receptor, voltage-gated calcium channels · NMDA receptor antagonist; calcium channel blocker · Voltage-gated calcium channels, NMDA receptor · Voltage-gated calcium channels, NMDA receptors · Neuromuscular junction (calcium channel antagonist at motor endplate) · Potassium ion (K+) / Na+/K+-ATPase pump · NMDA receptor, L-type calcium channels · NMDA receptor; voltage-gated calcium channels · NMDA receptor antagonist; calcium channel blocker (non-selective) · NMDA receptor antagonist; calcium channel modulator

Marketed (14)

• Magnesium Sulfate, Heptahydrate · University of Utah · Obstetrics, Neurology, Cardiology, Pulmonology
  Magnesium sulfate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuronal excitability and smooth muscle contractility.
• Natrium/ Kalium/ Magnesium sulfate · Tomas Bata Hospital, Czech Republic · Gastroenterology / Electrolyte management
  This combination of sodium, potassium, and magnesium sulfates acts as an osmotic laxative and electrolyte replacement therapy.
• Perioperative magnesium sulfate · Instituto Mexicano del Seguro Social · Perioperative medicine / Anesthesia
  Magnesium sulfate acts as a natural calcium antagonist and NMDA receptor antagonist, reducing neuromuscular excitability and vascular smooth muscle contractility.
• Sulfate, Magnesium · Assistance Publique - Hôpitaux de Paris · Neurology; Obstetrics; Gastroenterology; Emergency Medicine
  Magnesium sulfate acts as a central nervous system depressant and smooth muscle relaxant by blocking calcium influx and stabilizing neuronal membranes.
• Magnesium sulphate. · Ain Shams University · Obstetrics, Neurology, Gastroenterology, Emergency Medicine
  Magnesium sulphate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuromuscular excitability and vascular smooth muscle contractility.
• Magnesium sulfate 33% solution · The Baruch Padeh Medical Center, Poriya · Obstetrics, Neurology, Cardiovascular
  Magnesium sulfate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuronal excitability and smooth muscle contractility.
• Mg Cl · University of Vermont · Electrolyte/Mineral Supplementation
  Magnesium chloride is an electrolyte replacement that restores depleted magnesium levels in the body.
• Magnesium sulfate 12 hours · Instituto Materno Infantil Prof. Fernando Figueira · Obstetrics, Neurology
  Magnesium sulfate acts as a central nervous system depressant and anticonvulsant by blocking N-methyl-D-aspartate (NMDA) receptors and reducing neuromuscular transmission.
• Sterile Potassium Chloride Concentrate · The Queen Elizabeth Hospital · Electrolyte management / Critical care
  Potassium chloride replaces depleted potassium ions to restore normal serum potassium levels and maintain cellular and cardiac function.
• Magnesium sulfate IV · University of Liege · Obstetrics, Neurology, Cardiology
  Magnesium sulfate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuronal excitability and vascular smooth muscle contractility.
• Magnesium sulphate intramuscular · Nishtar Medical University · Obstetrics; Neurology; Cardiovascular
  Magnesium sulphate acts as a central nervous system depressant and anticonvulsant by blocking N-methyl-D-aspartate (NMDA) receptors and reducing neuromuscular transmission.
• Sodium 5mEq/kg/day · Hospital del Niño "Dr. Federico Gomez Santos" · Electrolyte/Metabolic disorders
  Sodium supplementation replaces or maintains serum sodium levels to correct hyponatremia or prevent sodium depletion.
• IV Magnesium Sulfate · University Hospitals Cleveland Medical Center · Obstetrics; Neurology; Cardiology; Pulmonology
  Magnesium sulfate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuronal excitability and vascular smooth muscle contractility.
• Magnesium Sulfate Infusion · Ondokuz Mayıs University · Obstetrics; Neurology; Critical Care
  Magnesium sulfate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuronal excitability and vascular smooth muscle contractility.

Phase 3 pipeline (2)

• Magnesium Sulfate low dose · University of Monastir · Neurology, Obstetrics, Cardiovascular
  Magnesium sulfate acts as a physiological calcium antagonist and NMDA receptor antagonist, reducing neuronal excitability and vascular smooth muscle contractility.
• Magnesium sulfate and then Digoxin · Sunnybrook Health Sciences Centre · Cardiovascular
  Magnesium sulfate reduces cardiac arrhythmias and electrolyte imbalance, while digoxin increases cardiac contractility and slows atrioventricular conduction.

Patent intelligence

• electrolyte supplement patent landscape — aggregated cliff calendar, attackable patents, originator estates