Topical liquid lidocaine — Competitive Intelligence Brief

Topical liquid lidocaine (Topical liquid lidocaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Oncology (supportive care).

marketed Local anesthetic Voltage-gated sodium channels Oncology (supportive care) Small molecule

Target snapshot

Topical liquid lidocaine (Topical liquid lidocaine) — OHSU Knight Cancer Institute. Lidocaine blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses to produce local anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Topical liquid lidocaine TARGET	Topical liquid lidocaine	OHSU Knight Cancer Institute	marketed	Local anesthetic	Voltage-gated sodium channels
Exparel Injectable Product	Exparel Injectable Product	Pacira Pharmaceuticals, Inc	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Bupivacaine and Dexamethasone Injection	Bupivacaine and Dexamethasone Injection	Colette Curtis MD	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)
Bupivacaine heavy and Morphine	Bupivacaine heavy and Morphine	Post Graduate Institute of Medical Education and Research, Chandigarh	marketed	Local anesthetic + opioid combination	Voltage-gated sodium channels (bupivacaine); mu-opioid receptor (morphine)
Betamethasone and local anesthetic	Betamethasone and local anesthetic	Jakob Møller Hansen, MD.	marketed	Corticosteroid with local anesthetic	Glucocorticoid receptor (betamethasone); voltage-gated sodium channels (local anesthetic component)
alkalinized lidocaine	alkalinized lidocaine	Massachusetts General Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Exparel Injectable Solution	Exparel Injectable Solution	The Cooper Health System	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class