Who are Tisseel Fibrin Sealant's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): TachoSil, Bioseal Fibrin Sealant, Fibrin Sealant (Artiss), Tachosil fibrin patch, Fibrin Sealant Grifols, Usage of Fibrin sealant.

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Last reviewed 2026-05-16 · How we verify

Tisseel Fibrin Sealant — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Tisseel Fibrin Sealant (Tisseel Fibrin Sealant) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Fibrin sealant. Area: Surgery/Hemostasis.

marketed Fibrin sealant Fibrinogen (substrate for thrombin-catalyzed polymerization) Surgery/Hemostasis Small molecule Live · refreshed every 30 min

Target snapshot

Tisseel Fibrin Sealant (Tisseel Fibrin Sealant) — Massachusetts General Hospital. Tisseel is a fibrin sealant that mimics the final step of the coagulation cascade to form a stable clot and seal tissue surfaces.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Tisseel Fibrin Sealant TARGET	Tisseel Fibrin Sealant	Massachusetts General Hospital	marketed	Fibrin sealant	Fibrinogen (substrate for thrombin-catalyzed polymerization)
TachoSil	TachoSil	GATT Technologies BV	marketed	Hemostatic agent / Fibrin sealant	Fibrinogen (conversion to fibrin via thrombin)
Bioseal Fibrin Sealant	Bioseal Fibrin Sealant	Ethicon, Inc.	marketed	Fibrin sealant / Hemostatic agent
Fibrin Sealant (Artiss)	Fibrin Sealant (Artiss)	Nguyen, Davis B., M.D.	marketed	Fibrin sealant	Fibrinogen; thrombin substrate
Tachosil fibrin patch	Tachosil fibrin patch	Ruhr University of Bochum	phase 3	Hemostatic agent; topical fibrin sealant patch	Fibrinogen; Factor II (thrombin)
Fibrin Sealant Grifols	Fibrin Sealant Grifols	Instituto Grifols, S.A.	phase 3	Fibrin sealant / Hemostatic agent	Fibrinogen (substrate for thrombin-catalyzed polymerization)
Usage of Fibrin sealant	Usage of Fibrin sealant	Samsung Medical Center	phase 3	Hemostatic agent / Fibrin sealant	Fibrinogen / Factor XIII

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Fibrin sealant class)

Baxter Healthcare Corporation · 2 drugs in this class
Massachusetts General Hospital · 1 drug in this class
Nguyen, Davis B., M.D. · 1 drug in this class
Nycomed · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tisseel Fibrin Sealant — Competitive Intelligence Brief. https://druglandscape.com/ci/tisseel-fibrin-sealant. Accessed 2026-05-16.

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