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Usage of Fibrin sealant

Samsung Medical Center · Phase 3 active Small molecule

Usage of Fibrin sealant is a Hemostatic agent / Fibrin sealant Small molecule drug developed by Samsung Medical Center. It is currently in Phase 3 development for Hemostasis and sealing of surgical wounds, Topical bleeding control during surgical procedures, Tissue adhesion and wound healing support.

Fibrin sealant forms a hemostatic plug by combining fibrinogen and thrombin to create a cross-linked fibrin clot that seals wounds and stops bleeding.

Fibrin sealant forms a hemostatic plug by combining fibrinogen and thrombin to create a cross-linked fibrin clot that seals wounds and stops bleeding. Used for Hemostasis and sealing of surgical wounds, Topical bleeding control during surgical procedures, Tissue adhesion and wound healing support.

At a glance

Generic nameUsage of Fibrin sealant
SponsorSamsung Medical Center
Drug classHemostatic agent / Fibrin sealant
TargetFibrinogen / Factor XIII
ModalitySmall molecule
Therapeutic areaSurgery / Hemostasis / Wound Management
PhasePhase 3

Mechanism of action

Fibrin sealant is a topical hemostatic agent composed of fibrinogen (or fibrin) and thrombin that mimics the final stages of the coagulation cascade. When applied to a bleeding surface, thrombin converts fibrinogen into fibrin monomers, which polymerize and cross-link to form a stable clot. This provides rapid hemostasis and can also serve as a tissue adhesive and scaffold for wound healing.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Usage of Fibrin sealant

What is Usage of Fibrin sealant?

Usage of Fibrin sealant is a Hemostatic agent / Fibrin sealant drug developed by Samsung Medical Center, indicated for Hemostasis and sealing of surgical wounds, Topical bleeding control during surgical procedures, Tissue adhesion and wound healing support.

How does Usage of Fibrin sealant work?

Fibrin sealant forms a hemostatic plug by combining fibrinogen and thrombin to create a cross-linked fibrin clot that seals wounds and stops bleeding.

What is Usage of Fibrin sealant used for?

Usage of Fibrin sealant is indicated for Hemostasis and sealing of surgical wounds, Topical bleeding control during surgical procedures, Tissue adhesion and wound healing support.

Who makes Usage of Fibrin sealant?

Usage of Fibrin sealant is developed by Samsung Medical Center (see full Samsung Medical Center pipeline at /company/samsung-medical-center).

What drug class is Usage of Fibrin sealant in?

Usage of Fibrin sealant belongs to the Hemostatic agent / Fibrin sealant class. See all Hemostatic agent / Fibrin sealant drugs at /class/hemostatic-agent-fibrin-sealant.

What development phase is Usage of Fibrin sealant in?

Usage of Fibrin sealant is in Phase 3.

What are the side effects of Usage of Fibrin sealant?

Common side effects of Usage of Fibrin sealant include Allergic reaction, Infection at application site, Thrombosis (rare), Immunogenicity.

What does Usage of Fibrin sealant target?

Usage of Fibrin sealant targets Fibrinogen / Factor XIII and is a Hemostatic agent / Fibrin sealant.

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