spinal administration of lidocaine — Competitive Intelligence Brief

spinal administration of lidocaine (spinal administration of lidocaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesiology.

phase 3 Local anesthetic Voltage-gated sodium channels Anesthesiology Small molecule

Target snapshot

spinal administration of lidocaine (spinal administration of lidocaine) — St. Antonius Hospital. Lidocaine blocks sodium channels in nerve cells, preventing the initiation and transmission of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
spinal administration of lidocaine TARGET	spinal administration of lidocaine	St. Antonius Hospital	phase 3	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine 0,5%	Levobupivacaine 0,5%	ASST Gaetano Pini-CTO	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
IV lignocaine bolus and infusion	IV lignocaine bolus and infusion	University of Auckland, New Zealand	marketed	Local anesthetic; Class IB antiarrhythmic agent	Voltage-gated sodium channels
lithium plus carbamazepine	lithium plus carbamazepine	University of Sao Paulo	marketed	Mood stabilizer combination	Lithium: inositol monophosphatase and GSK-3β; Carbamazepine: voltage-gated sodium channels
bupivacaine/ neostigmine.	bupivacaine/ neostigmine.	Ain Shams University	marketed	Local anesthetic combination	Voltage-gated sodium channels (bupivacaine); acetylcholinesterase (neostigmine)
Nerve block with Lidocain	Nerve block with Lidocain	Tehran University of Medical Sciences	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine plus adrenaline	Lidocaine plus adrenaline	University of Santiago de Compostela	marketed	Local anesthetic with vasopressor	Voltage-gated sodium channels; alpha-1 and beta-1 adrenergic receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class