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spinal administration of lidocaine
spinal administration of lidocaine is a Local anesthetic Small molecule drug developed by St. Antonius Hospital. It is currently in Phase 3 development for Local anesthesia for minor surgical procedures, epidural anesthesia for childbirth, and spinal anesthesia for surgical procedures.
Lidocaine blocks sodium channels in nerve cells, preventing the initiation and transmission of nerve impulses.
Lidocaine blocks sodium channels in nerve cells, preventing the initiation and transmission of nerve impulses. Used for Local anesthesia for minor surgical procedures, epidural anesthesia for childbirth, and spinal anesthesia for surgical procedures.
At a glance
| Generic name | spinal administration of lidocaine |
|---|---|
| Sponsor | St. Antonius Hospital |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 3 |
Mechanism of action
This action results in a temporary loss of sensation and motor function in the area where the lidocaine is administered. By blocking nerve impulses, lidocaine can help to reduce pain and discomfort in various medical procedures.
Approved indications
- Local anesthesia for minor surgical procedures, epidural anesthesia for childbirth, and spinal anesthesia for surgical procedures
Common side effects
- Numbness or tingling
- Headache
- Dizziness
- Nausea
Key clinical trials
- Transdiscal vs Paravertebral Neurolytic Splanchnic Nerve Block for Upper Abdominal Cancer Pain (NA)
- Efficacy of Sphenopalatine Block Compared to Blood Patch in the Management of Post-dural Puncture Headaches (PHASE3)
- Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery (NA)
- Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery (PHASE4)
- Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section (PHASE4)
- Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Cervicogenic Headache (NA)
- Comparison of Dural Puncture Epidural and Standard Epidural Anesthesia Techniques in Elective Cesarean Deliveries (NA)
- Quality Of Recovery After Pericapsular Nerve Group (PENG) Block For Hip Hemiarthroplasty Under Spinal Anesthesia (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- spinal administration of lidocaine CI brief — competitive landscape report
- spinal administration of lidocaine updates RSS · CI watch RSS
- St. Antonius Hospital portfolio CI
Frequently asked questions about spinal administration of lidocaine
What is spinal administration of lidocaine?
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Related
- Drug class: All Local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: St. Antonius Hospital — full pipeline
- Therapeutic area: All drugs in Anesthesiology
- Indication: Drugs for Local anesthesia for minor surgical procedures, epidural anesthesia for childbirth, and spinal anesthesia for surgical procedures