Scalp block with 0.5% plain Marcaine — Competitive Intelligence Brief

Scalp block with 0.5% plain Marcaine (Scalp block with 0.5% plain Marcaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide). Area: Anesthesia.

marketed Local anesthetic (amide) Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Scalp block with 0.5% plain Marcaine (Scalp block with 0.5% plain Marcaine) — Chiang Mai University. Bupivacaine blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Scalp block with 0.5% plain Marcaine TARGET	Scalp block with 0.5% plain Marcaine	Chiang Mai University	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Ropivacaine concentration low	Ropivacaine concentration low	Oslo University Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine continuous infusion	Levobupivacaine continuous infusion	Fondazione IRCCS Policlinico San Matteo di Pavia	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Extended Phenytoin Sodium	Extended Phenytoin Sodium	Bristol-Myers Squibb	marketed	Aromatic antiepileptic drug (hydantoin)	Voltage-gated sodium channels
Levobupivacaine lidocaine spinal anesthesia	Levobupivacaine lidocaine spinal anesthesia	Diskapi Teaching and Research Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Nerve block with Lidocain	Nerve block with Lidocain	Tehran University of Medical Sciences	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine Hcl 0.75% Inj	Bupivacaine Hcl 0.75% Inj	Rothman Institute Orthopaedics	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide) class)

1. Poznan University of Medical Sciences · 4 drugs in this class
2. Nantes University Hospital · 3 drugs in this class
3. Bozyaka Training and Research Hospital · 2 drugs in this class
4. ASST Gaetano Pini-CTO · 2 drugs in this class
5. Centre Hospitalier Universitaire de Nīmes · 1 drug in this class
6. Chiang Mai University · 1 drug in this class
7. Beijing Tiantan Hospital · 1 drug in this class
8. Complejo Hospitalario Universitario de Granada · 1 drug in this class
9. Ciusss de L'Est de l'Île de Montréal · 1 drug in this class
10. China Medical University, China · 1 drug in this class