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Scalp block with 0.5% plain Marcaine

Chiang Mai University · FDA-approved active Small molecule

Scalp block with 0.5% plain Marcaine is a Local anesthetic (amide) Small molecule drug developed by Chiang Mai University. It is currently FDA-approved for Local anesthesia for scalp procedures and surgery. Also known as: Code 1.

Bupivacaine blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia.

Bupivacaine blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia. Used for Local anesthesia for scalp procedures and surgery.

At a glance

Generic nameScalp block with 0.5% plain Marcaine
Also known asCode 1
SponsorChiang Mai University
Drug classLocal anesthetic (amide)
TargetVoltage-gated sodium channels
ModalitySmall molecule
Therapeutic areaAnesthesia
PhaseFDA-approved

Mechanism of action

Bupivacaine is a long-acting amide local anesthetic that reversibly inhibits sodium influx through voltage-gated sodium channels in nerve cell membranes. This prevents depolarization and conduction of nerve impulses, resulting in local anesthesia. When administered as a scalp block, it anesthetizes the sensory nerves of the scalp to prevent pain during surgical procedures.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Scalp block with 0.5% plain Marcaine

What is Scalp block with 0.5% plain Marcaine?

Scalp block with 0.5% plain Marcaine is a Local anesthetic (amide) drug developed by Chiang Mai University, indicated for Local anesthesia for scalp procedures and surgery.

How does Scalp block with 0.5% plain Marcaine work?

Bupivacaine blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia.

What is Scalp block with 0.5% plain Marcaine used for?

Scalp block with 0.5% plain Marcaine is indicated for Local anesthesia for scalp procedures and surgery.

Who makes Scalp block with 0.5% plain Marcaine?

Scalp block with 0.5% plain Marcaine is developed and marketed by Chiang Mai University (see full Chiang Mai University pipeline at /company/chiang-mai-university).

Is Scalp block with 0.5% plain Marcaine also known as anything else?

Scalp block with 0.5% plain Marcaine is also known as Code 1.

What drug class is Scalp block with 0.5% plain Marcaine in?

Scalp block with 0.5% plain Marcaine belongs to the Local anesthetic (amide) class. See all Local anesthetic (amide) drugs at /class/local-anesthetic-amide.

What development phase is Scalp block with 0.5% plain Marcaine in?

Scalp block with 0.5% plain Marcaine is FDA-approved (marketed).

What are the side effects of Scalp block with 0.5% plain Marcaine?

Common side effects of Scalp block with 0.5% plain Marcaine include Injection site pain or discomfort, Transient paresthesia, Systemic toxicity (if absorbed in high concentrations), Allergic reaction (rare with amide local anesthetics).

What does Scalp block with 0.5% plain Marcaine target?

Scalp block with 0.5% plain Marcaine targets Voltage-gated sodium channels and is a Local anesthetic (amide).

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