Proparacaine Ophthalmic — Competitive Intelligence Brief

Proparacaine Ophthalmic (Proparacaine Ophthalmic) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (ester). Area: Ophthalmology.

marketed Local anesthetic (ester) Voltage-gated sodium channels Ophthalmology Small molecule

Target snapshot

Proparacaine Ophthalmic (Proparacaine Ophthalmic) — American Genomics, LLC. Proparacaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission in the eye.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Proparacaine Ophthalmic TARGET	Proparacaine Ophthalmic	American Genomics, LLC	marketed	Local anesthetic (ester)	Voltage-gated sodium channels
Intravenous Lidocaine infusion + Standard Anesthesia	Intravenous Lidocaine infusion + Standard Anesthesia	Instituto Mexicano del Seguro Social	marketed	Local anesthetic (sodium channel blocker)	Voltage-gated sodium channels
IV lignocaine bolus and infusion	IV lignocaine bolus and infusion	University of Auckland, New Zealand	marketed	Local anesthetic; Class IB antiarrhythmic agent	Voltage-gated sodium channels
Infiltration - EXPAREL	Infiltration - EXPAREL	Pacira Pharmaceuticals, Inc	marketed	Long-acting local anesthetic	Voltage-gated sodium channels
Anesthetics, Local	Anesthetics, Local	University of Alberta	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine and Fentanyl	Levobupivacaine and Fentanyl	Hamad Medical Corporation	marketed	Local anesthetic with opioid analgesic combination	Voltage-gated sodium channels; mu-opioid receptor
Liposome bupivacaine	Liposome bupivacaine	Catherine Vandepitte, M.D.	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (ester) class)

1. Sintetica SA · 4 drugs in this class
2. Centre Hospitalier Universitaire Saint Pierre · 1 drug in this class
3. Nova Scotia Health Authority · 1 drug in this class
4. American Genomics, LLC · 1 drug in this class
5. University of Miami · 1 drug in this class
6. Wenzhou Medical University · 1 drug in this class
7. Oregon Health and Science University · 1 drug in this class