Prilocaine (Hyperbaric 2%) — Competitive Intelligence Brief

Prilocaine (Hyperbaric 2%) (Prilocaine (Hyperbaric 2%)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Prilocaine (Hyperbaric 2%) (Prilocaine (Hyperbaric 2%)) — Guy's and St Thomas' NHS Foundation Trust. Prilocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Prilocaine (Hyperbaric 2%) TARGET	Prilocaine (Hyperbaric 2%)	Guy's and St Thomas' NHS Foundation Trust	marketed	Local anesthetic	Voltage-gated sodium channels
dyclonine hydrochloride only	dyclonine hydrochloride only	Peking Union Medical College Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
phenytoin and probenecid	phenytoin and probenecid	Jim McAuley	marketed	Anticonvulsant and uricosuric agent combination	Voltage-gated sodium channels (phenytoin); organic acid transporter (probenecid)
Marcaine 0.25 % Injectable Solution	Marcaine 0.25 % Injectable Solution	Connecticut Children's Medical Center	marketed	Local anesthetic	Voltage-gated sodium channels
L:Lidocaine	L:Lidocaine	B.P. Koirala Institute of Health Sciences	marketed	Local anesthetic	Voltage-gated sodium channels
Spinal Anesthesia	Spinal Anesthesia	Samuel Lunenfeld Research Institute, Mount Sinai Hospital	marketed	Local anesthetic (regional anesthesia technique)	Voltage-gated sodium channels in nerve membranes
MEPIVACAÍNE	MEPIVACAÍNE	Complexo Hospitalario Universitario de A Coruña	marketed	Local anesthetic (amide)	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class