Lidocaine-Prilocaine Cream 2.5-2.5% — Competitive Intelligence Brief

Lidocaine-Prilocaine Cream 2.5-2.5% (Lidocaine-Prilocaine Cream 2.5-2.5%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia/Pain Management.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia/Pain Management Small molecule

Target snapshot

Lidocaine-Prilocaine Cream 2.5-2.5% (Lidocaine-Prilocaine Cream 2.5-2.5%) — Centre Hospitalier le Mans. Lidocaine and prilocaine are local anesthetics that block sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Lidocaine-Prilocaine Cream 2.5-2.5% TARGET	Lidocaine-Prilocaine Cream 2.5-2.5%	Centre Hospitalier le Mans	marketed	Local anesthetic	Voltage-gated sodium channels
Lacosamide - rapid titration 2	Lacosamide - rapid titration 2	Seoul National University Hospital	marketed	Anticonvulsant; sodium channel modulator	Voltage-gated sodium channels; CRMP-2
Isobaric 2-chloroprocaine	Isobaric 2-chloroprocaine	Centre Hospitalier Universitaire Saint Pierre	marketed	Local anesthetic (ester)	Voltage-gated sodium channels
isobaric mepivacaine	isobaric mepivacaine	Thomas Jefferson University	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Bupivacaine-fentanyl emergency group	Bupivacaine-fentanyl emergency group	Conrad Arnfinn Bjørshol	marketed	Local anesthetic + opioid analgesic combination	Voltage-gated sodium channels (bupivacaine); mu opioid receptor (fentanyl)
Carbamazepine-Implant	Carbamazepine-Implant	University of Sao Paulo	marketed	Anticonvulsant / Antiepileptic agent	Voltage-gated sodium channels
Prilocaine (Hyperbaric 2%)	Prilocaine (Hyperbaric 2%)	Guy's and St Thomas' NHS Foundation Trust	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class