Lidocaïne 2% — Competitive Intelligence Brief

Lidocaïne 2% (Lidocaïne 2%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Lidocaïne 2% (Lidocaïne 2%) — University of Liege. Lidocaine blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Lidocaïne 2% TARGET	Lidocaïne 2%	University of Liege	marketed	Local anesthetic	Voltage-gated sodium channels
Buffered Articaine Hydrochloride + Epinephrine	Buffered Articaine Hydrochloride + Epinephrine	Ohio State University	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-1 adrenergic receptors (epinephrine component)
Transdermal Lidocaine Patch	Transdermal Lidocaine Patch	University of Wisconsin, Madison	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine 0.5% + epinephrin 1/200000	Levobupivacaine 0.5% + epinephrin 1/200000	University Hospital, Antwerp	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-adrenergic receptors
Anesthetic Topical Adhesive Synera	Anesthetic Topical Adhesive Synera	Brown, Theodore R., M.D., MPH	marketed	Topical local anesthetic	Voltage-gated sodium channels
Ropivacaine concentration low	Ropivacaine concentration low	Oslo University Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Articaine Hydrochloride + Epinephrine	Articaine Hydrochloride + Epinephrine	Ankara Yildirim Beyazıt University	marketed	Local anesthetic with vasoconstrictor	Voltage-gated sodium channels; alpha-1 adrenergic receptors (epinephrine component)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class