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Anesthetic Topical Adhesive Synera
Anesthetic Topical Adhesive Synera is a Topical local anesthetic Small molecule drug developed by Brown, Theodore R., M.D., MPH. It is currently FDA-approved for Topical anesthesia for minor dermatological procedures (e.g., venipuncture, IV catheter insertion, laser procedures), Superficial skin procedures requiring local anesthesia. Also known as: Synera.
Synera is a topical anesthetic patch that delivers lidocaine and tetracaine through the skin to numb the area before minor procedures.
Synera is a topical anesthetic patch that delivers lidocaine and tetracaine through the skin to numb the area before minor procedures. Used for Topical anesthesia for minor dermatological procedures (e.g., venipuncture, IV catheter insertion, laser procedures), Superficial skin procedures requiring local anesthesia.
At a glance
| Generic name | Anesthetic Topical Adhesive Synera |
|---|---|
| Also known as | Synera |
| Sponsor | Brown, Theodore R., M.D., MPH |
| Drug class | Topical local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
Synera combines two local anesthetics—lidocaine and tetracaine—in a eutectic mixture formulation applied as a patch. The patch uses heat activation to enhance percutaneous penetration of these anesthetics into the dermis and subcutaneous tissue, blocking sodium channels in nerve fibers to produce local anesthesia without systemic absorption.
Approved indications
- Topical anesthesia for minor dermatological procedures (e.g., venipuncture, IV catheter insertion, laser procedures)
- Superficial skin procedures requiring local anesthesia
Common side effects
- Erythema at application site
- Edema at application site
- Blanching of skin
- Mild burning or irritation
Key clinical trials
- Anesthetic Topical Adhesive (Synera™) to Reduce Injection Pain With Subcutaneous Multiple Sclerosis Medications (PHASE4)
- Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Anesthetic Topical Adhesive Synera CI brief — competitive landscape report
- Anesthetic Topical Adhesive Synera updates RSS · CI watch RSS
- Brown, Theodore R., M.D., MPH portfolio CI
Frequently asked questions about Anesthetic Topical Adhesive Synera
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Related
- Drug class: All Topical local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: Brown, Theodore R., M.D., MPH — full pipeline
- Therapeutic area: All drugs in Anesthesia/Pain Management
- Indication: Drugs for Topical anesthesia for minor dermatological procedures (e.g., venipuncture, IV catheter insertion, laser procedures)
- Indication: Drugs for Superficial skin procedures requiring local anesthesia
- Also known as: Synera
- Compare: Anesthetic Topical Adhesive Synera vs similar drugs
- Pricing: Anesthetic Topical Adhesive Synera cost, discount & access