Levobupivacaine lidocaine spinal anesthesia — Competitive Intelligence Brief

Levobupivacaine lidocaine spinal anesthesia (Levobupivacaine lidocaine spinal anesthesia) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Levobupivacaine lidocaine spinal anesthesia (Levobupivacaine lidocaine spinal anesthesia) — Diskapi Teaching and Research Hospital. Levobupivacaine and lidocaine are local anesthetics that block sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce reversible loss of sensation.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Levobupivacaine lidocaine spinal anesthesia TARGET	Levobupivacaine lidocaine spinal anesthesia	Diskapi Teaching and Research Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Qudexy XR	Qudexy XR	Upsher-Smith Laboratories	marketed	Anticonvulsant / Antiepileptic agent	GABA-A receptor; voltage-gated sodium channels
Lidocaine-Prilocaine Cream 2.5-2.5%	Lidocaine-Prilocaine Cream 2.5-2.5%	Centre Hospitalier le Mans	marketed	Local anesthetic	Voltage-gated sodium channels
Articaine / EPINEPHrine Cartridge	Articaine / EPINEPHrine Cartridge	Universidad de Antioquia	marketed	Local anesthetic with vasopressor	Voltage-gated sodium channels (articaine); alpha-1 and beta-1 adrenergic receptors (epinephrine)
nortriptyline + topiramate	nortriptyline + topiramate	University of California, Irvine	marketed	Tricyclic antidepressant + anticonvulsant combination	Norepinephrine transporter, serotonin transporter, voltage-gated sodium channels, GABA receptors
extraarticular injection with ropivacaine	extraarticular injection with ropivacaine	Hvidovre University Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Lidocaine skin wheal	Lidocaine skin wheal	George Washington University	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class