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extraarticular injection with ropivacaine
Ropivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia.
Ropivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the initiation and propagation of action potentials to produce local anesthesia. Used for Local anesthesia for extraarticular procedures and pain management.
At a glance
| Generic name | extraarticular injection with ropivacaine |
|---|---|
| Sponsor | Hvidovre University Hospital |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Anesthesia/Pain Management |
| Phase | FDA-approved |
Mechanism of action
Ropivacaine is an amide-type local anesthetic that reversibly inhibits sodium influx through voltage-gated sodium channels in nerve cell membranes. This prevents depolarization and blocks nerve conduction in the injected area. When administered as an extraarticular injection, it provides localized anesthesia and analgesia at the injection site and surrounding tissues.
Approved indications
- Local anesthesia for extraarticular procedures and pain management
Common side effects
- Injection site pain or discomfort
- Transient numbness or paresthesia
- Systemic toxicity (rare, with overdose)
- Allergic reactions (rare)
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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