Who are Ketamine with propofol's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lidocaine/Magnesium, Lidocaine 7% + Tetracaine 7% cream, Triamcinolone + Lidocaine, Normal saline, Lidocaine, dexmetomidine, Anesthesia maintenance , propofol,remifentanil,cisatracurium, midazolam,fentanyl,etomidate,Cisatracurium besylate.

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Last reviewed 2026-06-10 · How we verify

Ketamine with propofol — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ketamine with propofol (Ketamine with propofol) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anesthetic combination. Area: Anesthesiology.

marketed Anesthetic combination NMDA receptor (ketamine); GABA-A receptor (propofol) Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

Ketamine with propofol (Ketamine with propofol) — Henry M. Jackson Foundation for the Advancement of Military Medicine. Ketamine and propofol together provide rapid-onset anesthesia and analgesia by blocking NMDA receptors and enhancing GABAergic inhibition, respectively.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Ketamine with propofol TARGET	Ketamine with propofol	Henry M. Jackson Foundation for the Advancement of Military Medicine	marketed	Anesthetic combination	NMDA receptor (ketamine); GABA-A receptor (propofol)
Lidocaine/Magnesium	Lidocaine/Magnesium	University of Wisconsin, Madison	marketed	Local anesthetic combination	Voltage-gated sodium channels; NMDA receptor
Lidocaine 7% + Tetracaine 7% cream	Lidocaine 7% + Tetracaine 7% cream	Galderma R&D	marketed	Local anesthetic combination	Voltage-gated sodium channels
Triamcinolone + Lidocaine	Triamcinolone + Lidocaine	MetroHealth Medical Center	marketed	Corticosteroid + Local anesthetic combination	Glucocorticoid receptor (triamcinolone); voltage-gated sodium channels (lidocaine)
Normal saline, Lidocaine, dexmetomidine	Normal saline, Lidocaine, dexmetomidine	Kasr El Aini Hospital	marketed	Local anesthetic combination with sedative-analgesic agent	Voltage-gated sodium channels (lidocaine); alpha-2 adrenergic receptors (dexmedetomidine)
Anesthesia maintenance , propofol,remifentanil,cisatracurium	Anesthesia maintenance , propofol,remifentanil,cisatracurium	Second Affiliated Hospital of Xi'an Jiaotong University	marketed	General anesthetic combination (GABA-A agonist + opioid + neuromuscular blocker)	GABA-A receptor (propofol); mu-opioid receptor (remifentanil); nicotinic acetylcholine receptor at neuromuscular junction (cisatracurium)
midazolam,fentanyl,etomidate,Cisatracurium besylate	midazolam,fentanyl,etomidate,Cisatracurium besylate	First Affiliated Hospital Xi'an Jiaotong University	marketed	Anesthetic combination (benzodiazepine, opioid, hypnotic, neuromuscular blocker)	GABA-A receptor (midazolam, etomidate), mu opioid receptor (fentanyl), nicotinic acetylcholine receptor at neuromuscular junction (cisatracurium)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anesthetic combination class)

Henry M. Jackson Foundation for the Advancement of Military Medicine · 1 drug in this class
Kasr El Aini Hospital · 1 drug in this class
Universidad de Cartagena · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ketamine with propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/ketamine-with-propofol. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing