intrarectal lidocaine gel — Competitive Intelligence Brief

intrarectal lidocaine gel (intrarectal lidocaine gel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Gastroenterology.

marketed Local anesthetic Voltage-gated sodium channels Gastroenterology Small molecule

Target snapshot

intrarectal lidocaine gel (intrarectal lidocaine gel) — Bagcilar Training and Research Hospital. Lidocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
intrarectal lidocaine gel TARGET	intrarectal lidocaine gel	Bagcilar Training and Research Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine-fentanyl emergency group	Bupivacaine-fentanyl emergency group	Conrad Arnfinn Bjørshol	marketed	Local anesthetic + opioid analgesic combination	Voltage-gated sodium channels (bupivacaine); mu opioid receptor (fentanyl)
Intra-articular Lidocaine	Intra-articular Lidocaine	University of Central Florida	marketed	Local anesthetic	Voltage-gated sodium channels
Instillation - EXPAREL	Instillation - EXPAREL	Pacira Pharmaceuticals, Inc	marketed	Long-acting local anesthetic	Voltage-gated sodium channels
isobaric mepivacaine	isobaric mepivacaine	Thomas Jefferson University	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Isobaric 2-chloroprocaine	Isobaric 2-chloroprocaine	Centre Hospitalier Universitaire Saint Pierre	marketed	Local anesthetic (ester)	Voltage-gated sodium channels
Generic lamotrigine	Generic lamotrigine	University of Maryland, Baltimore	marketed	Anticonvulsant / Mood stabilizer	Voltage-gated sodium channels; glutamate release inhibition

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class