Hyperbaric Levobupivacaine 0.75% — Competitive Intelligence Brief

Hyperbaric Levobupivacaine 0.75% (Hyperbaric Levobupivacaine 0.75%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide class). Area: Anesthesia.

marketed Local anesthetic (amide class) Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Hyperbaric Levobupivacaine 0.75% (Hyperbaric Levobupivacaine 0.75%) — Fundacion Clinica Valle del Lili. Levobupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and propagation of action potentials.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Hyperbaric Levobupivacaine 0.75% TARGET	Hyperbaric Levobupivacaine 0.75%	Fundacion Clinica Valle del Lili	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Ropivacaine/Fentanyl	Ropivacaine/Fentanyl	National Institute for Tuberculosis and Lung Diseases, Poland	marketed	Local anesthetic with opioid analgesic combination	Voltage-gated sodium channels (ropivacaine); mu opioid receptor (fentanyl)
Perineural Dexamethasone and bupivacaine	Perineural Dexamethasone and bupivacaine	Sherif Mohamed Abd el moneim Soaida, MD	marketed	Local anesthetic with adjuvant corticosteroid	Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)
Levobupivacaine wound infiltration	Levobupivacaine wound infiltration	University of Genova	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Lidocaine-chlorprocaine combination	Lidocaine-chlorprocaine combination	Hadassah Medical Organization	marketed	Local anesthetic combination	Voltage-gated sodium channels
Lidocaine HCl 1%	Lidocaine HCl 1%	HaEmek Medical Center, Israel	marketed	Local anesthetic	Voltage-gated sodium channels
Adjunctive Zonisamide	Adjunctive Zonisamide	Eisai Inc.	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide class) class)

1. Ain Shams University · 2 drugs in this class
2. Başakşehir Çam & Sakura City Hospital · 2 drugs in this class
3. TriHealth Inc. · 2 drugs in this class
4. Centre of Postgraduate Medical Education · 2 drugs in this class
5. Bozyaka Training and Research Hospital · 2 drugs in this class
6. Complejo Hospitalario Universitario de Granada · 1 drug in this class
7. Clinique Saint-Jean, Bruxelles · 1 drug in this class
8. Hospital Clínico Universitario de Valencia · 1 drug in this class
9. Fundacion Clinica Valle del Lili · 1 drug in this class
10. Federal University of Minas Gerais · 1 drug in this class